Motor Neuron Disease

Motor Neuron Disease (MND) Motor Neuron Diseases (MNDs) are neurodegenerative diseases characterised by progressive selective loss of upper motor neurons (motor cortex and cranial nerve nuclei) and lower motor neurons (anterior horn cells). The diseases are purely motor with sensation…

Guillain-Barre Syndrome

Guillain-Barre Syndrome (GBS) Guillain-Barré Syndrome (GBS) is a heterogeneous group of conditions characterised by immune-mediated destruction of peripheral nerves (cranial nerves can be involved as well). Acute paralysis and diminished tendon reflexes are hallmarks of the condition. GBS is a…

Parkinson Disease

Parkinson Disease Parkinson’s disease is a progressive neurodegenerative disorder that results in abnormalities in movement, autonomic function and cognition. It is caused by degeneration of dopaminergic neurons in the substantia nigra pars compacta, a nucleus that is involved in the…

Stroke Syndromes

Overview Major regions of stroke Region Area supplied Function MCA Lateral frontal lobes, temporal lobes, lateral anterior parietal lobes Upper body, language ACA Mesial and anterior frontal lobes, medial parietal lobes Lower body, pelvic floor musculature, sensory integration Ophthalmic artery…

Status Epilepticus

Status Epilepticus This is a protracted seizure. By definition, status epilepticus is a seizure that has lasted for > 30 minutes without intervening consciousness (but in reality, it is considered if a seizure lasts > 5 minutes). The most common…