Gartner’s Duct Cyst

A Gartner’s duct cyst forms when the Wolffian duct does not fully involute. It is usually asymptomatic, commonly being discovered incidentally on a transvaginal ultrasound. It is located on the anterolateral wall of the proximal vagina. Other cystic anomalies in the female…

Atrophic Vaginitis

Atrophic vaginitis is the thinning of the vaginal epithelium due to decreased oestrogen levels. It is very common in post-menopausal women. It can also occur in functionally post-menopausal women, i.e., following a bilateral salpingo-ophorectomy.

Vaginal Septum

Types of vaginal septa Septum Description Transverse vaginal septum This is due to incomplete fusion of the mullerian duct and urogenital sinus. It presents as primary amenorrhea (”cryptomenorrhea”) due to uterine outflow obstruction – cyclical lower abdominal pain, amenorrhea, central pelvic mass…

Nephrotoxins

Nephrotoxins are substances that damage the kidney tubules directly or indirectly. Indirect damage may be due to interstitial nephritis. Examples of nephrotoxins Category Examples Nota bene Analgesics NSAIDS, aspirin and paracetamol This is often silent until advanced CKD Antibiotics Aminoglycosides,…

Tubulointerstitial Nephritis

Tubulointerstitial nephritis is inflammation of the tubules and interstitial spaces. Drug-induced interstitial nephritis is the most important cause. It can occur at any age and may develop even after prolonged exposure. Its incidence peaks between the years 60 and 70. Classification Classification…

Minimal Change Disease

Minimal change disease is a nephrotic syndrome characterised by the absence of significant histological abnormalities on light microscopy, with podocyte effacement visible on electron microscopy. It peaks between ages 1 and 5, and affects boys and girls equally.

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