Mycobacterium

In a tabular format, list the difference between primary and post-primary TB lesions Primary Post-primary Local lesion Small Large Lymphatic involvement Yes Minimal Cavity formation Rare Frequent Tuberculin reactivity Initially negative Positive Infectivity Uncommon Usual Site Any Apical region Local…

Gram Positive Bacilli

Bacillus Clostridium Compare and contrast the paralysis caused by Clostridium botulinum and Clostridium tetani Tetanus Botulism Toxin Tetanospasmin and tetanolysin Botulinum toxin MOA Cleaves SNARE proteins in Renshaw cells to cause unhibited a-motor neuron contraction Cleaves SNARE proteins in a-motor…

Gram Positive Cocci

Staphylococci Choose one clinical condition associated with Staphylococcus aureus and discuss its pathogenesis, clinical manifestations, laboratory diagnosis and antimicrobial treatment. Clinical condition Pathogenesis Clinical manifestations 1. Toxic Shock Syndrome Females using tampons, individuals with wounds, patients with nasal packaging, TSST-1…

Introduction to Bacteriology

What are the differences between prokaryotes and eukaryotes? Prokaryotes Eukaryotes Circular DNA without proteins Complex of DNA with proteins Nucleoid and plasma Nucleus and mitochondrial DNA Ribosomes are absent Ribosomes are present Cytoplasmic organelles are absent Cytoplasmic organelles are present…

Guillain-Barre Syndrome

Overview Guillain-Barre Syndrome (GBS) is a heterogenous group of conditions characterised by immune-mediated destruction of peripheral nerves (cranial nerves can be involved as well). Acute paralysis and diminished tendon reflexes are a hallmark for the condition. Commonly, symptoms arise after…

Stroke

Overview A stroke is a sudden onset of brain dysfunction caused by an altered cerebrovascular blood supply. It is acute in onset and presents with focal neurological deficits (95% of the time). It is a clinical diagnosis, which requires imaging…

Approach to Hematuria

Overview Hematuria can be simply defined as the presence of blood in urine which is indicative of bleeding along the urinary tract. According to the National Institutes of Health, it can be further defined as the presence of at least…

Respiratory Infections

Overview Respiratory infection Description Bronchitis Inflammation of the airway. Predisposition in COPD. Pulmonary abscess Abscess of the pulmonary tissue. Predisposition in aspiration, loss of consciousness, poor dentition Pneumonia Infection of the lung parenchyma Common Causative Organisms