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Hyperexcision

November 2024: Foundation

  • OnJuly 27, 2025
  • InAdvanced / Pulse Check

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TOTW #54 – Biochemistry

  • OnMay 18, 2025
  • InBiochemistry / TOTW

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TOTW #53 – Haematology

  • OnMay 10, 2025
  • InHaematology / TOTW

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TOTW #52 – Embryology

  • OnMay 3, 2025
  • InEmbryology / TOTW

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DIVERSIFIED PATHS TOWARDS AND FROM HEALTH CARE

  • OnApril 28, 2025
  • InBlog / Productivity / Slice of Life / Wellness / White Coat Affairs

From inability to leave well alone, From too much zeal for what is new and contempt for what is old,  From putting knowledge before wisdom, science before art, cleverness before common sense,  From treating patients as cases, and  From making…

TOTW #51 – Child Health and Paediatrics

  • OnApril 27, 2025
  • InPaediatrics / TOTW

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Adnexal Torsion

  • OnApril 25, 2025
  • InCheat Sheets / Obstetrics and Gynaecology

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Abnormal Uterine Bleeding (AUB)

  • OnApril 25, 2025
  • InCheat Sheets / Obstetrics and Gynaecology

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Menopause

  • OnApril 25, 2025
  • InCheat Sheets / Obstetrics and Gynaecology

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Gonorrhoeal and Chlamydial Infection

  • OnApril 25, 2025
  • InCheat Sheets / Infectious Disease / Obstetrics and Gynaecology

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REFERENCE INTERVALS

Biochemistry
Adrenocorticotrophic hormoneP: <80 ng/L
Alanine aminotransferase (ALT)P: 5–35 U/L
AlbuminP: 35–50 g/L
AldosteroneP: 100–500 pmol/L
Alkaline phosphataseP: 30–130 U/L (adults)
α-AmylaseP: 0–180 IU/dL
α-FetoproteinS: <10 kU/L
Angiotensin IIP: 5–35 pmol/L
Antidiuretic hormone (ADH)P: 0.9–4.6 pmol/L
Aspartate transaminaseP: 5–35 U/L
BicarbonateP: 24–30 mmol/L
BilirubinP: 3–17 μmol/L
BNPP: <50 ng/L
C-reactive proteinP: <10 mg/L
CalcitoninP: <0.1 mcg/L
Calcium (ionized)P: 1.0–1.25 mmol/L
Calcium (total)P: 2.12–2.60 mmol/L
ChlorideP: 95–105 mmol/L
CholesterolP: <5.0 mmol/L
VLDLP: 0.128–0.645 mmol/L
LDLP: <2.0 mmol/L
HDLP: 0.9–1.93 mmol/L
CortisolP: AM 450–700 nmol/L, Midnight 80–280 nmol/L
Creatine kinase (CK)P: ♂ 25–195 U/L, ♀ 25–170 U/L
CreatinineP: 70–100 μmol/L
FerritinP: 12–200 mcg/L
FolateS: 2.1 mcg/L
FSHP/S: 2–8 U/L ♂ (luteal); >25 U/L menopause
Gamma-glutamyl transpeptidaseP: ♂ 11–51 U/L, ♀ 7–33 U/L
Glucose (fasting)P: 3.5–5.5 mmol/L
Growth hormoneP: <20 mu/L
HbA1C (DCCT)B: 4–6%
HbA1C (IFCC)B: 20–42 mmol/mol
IronS: ♂ 14–31 μmol/L, ♀ 11–30 μmol/L
LactateP: Venous 0.6–2.4 mmol/L, Arterial 0.6–1.8 mmol/L
Lactate dehydrogenase (LDH)P: 70–250 U/L
LeadB: <1.8 mmol/L
LHP: 3–16 U/L (luteal)
MagnesiumP: 0.75–1.05 mmol/L
OsmolalityP: 278–305 mosmol/kg
Parathyroid hormone (PTH)P: 0.8–8.5 pmol/L
PotassiumP: 3.5–5.3 mmol/L
ProlactinP: ♂ <450 U/L, ♀ <600 U/L
PSAP: 0–4 mcg/mL
Protein (total)P: 60–80 g/L
Red cell folateB: 0.36–1.44 μmol/L
ReninP: Erect 2.8–4.5, Recumbent 1.1–2.7 pmol/mL/h
SodiumP: 135–145 mmol/L
TBGP: 7–17 mg/L
TSHP: 0.5–4.2 mU/L
Thyroxine (T4)P: 70–140 nmol/L
Free T4P: 9–22 pmol/L
Total iron-binding capacityS: 54–75 μmol/L
Triglycerides (fasting)P: 0.50–2.3 mmol/L
Triiodothyronine (T3)P: 1.2–3.0 nmol/L
Troponin TP: <0.1 mcg/L
UrateP: ♂ 210–480 μmol/L, ♀ 150–390 μmol/L
UreaP: 2.5–6.7 mmol/L
Vitamin B12S: 0.13–0.68 nmol/L
Vitamin DS: 50 nmol/L
Arterial Blood Gases
pH7.35–7.45
PaCO₂4.7–6.0 kPa
PaO₂>10.6 kPa
Base excess±2 mmol/L
Urine
Cortisol (free)<280 nmol/24h
Hydroxyindole acetic acid16–73 μmol/24h
Hydroxymethylmandelic acid16–48 μmol/24h
Metanephrines0.03–0.69 μmol/mmol creatinine
Osmolality350–1000 mosmol/kg
17-Oxogenic steroids♂ 28–30 μmol/24h, ♀ 21–66 μmol/24h
17-Oxosteroids (neutral)♂ 17–76 μmol/24h, ♀ 14–59 μmol/24h
Phosphate (inorganic)15–50 mmol/24h
Potassium14–120 mmol/24h
Protein<150 mg/24h
Protein/creatinine ratio<3 mg/mmol
Sodium100–250 mmol/24h
Haematology
WCC4.0–11.0 ×10⁹/L
Red cell count♂ 4.5–6.5 ×10¹²/L, ♀ 3.9–5.6 ×10¹²/L
Haemoglobin♂ 130–180 g/L, ♀ 115–160 g/L
PCV / Haematocrit♂ 0.4–0.54 L/L, ♀ 0.37–0.47 L/L
MCV76–96 fL
MCH27–32 pg
MCHC300–360 g/L
RDW11.6–14.6%
Neutrophils2.0–7.5 ×10⁹/L (40–75%)
Lymphocytes1.0–4.5 ×10⁹/L (20–45%)
Eosinophils0.04–0.44 ×10⁹/L (1–6%)
Basophils0–0.10 ×10⁹/L (0–1%)
Monocytes0.2–0.8 ×10⁹/L (2–10%)
Platelet count150–400 ×10⁹/L
Reticulocyte count0.8–2.0% / 25–100 ×10⁹/L
ESRDepends on age
Prothrombin time10–14 s
APTT35–45 s
Paediatric
Pulse Rate (beats per minute)
Neonate (<1 month)140–160
Infant (<1 year)120–140
1–5 years110–130
5–12 years80–120
>12 years70–100
Temperature
Normal range36.6–37.2 °C
38.0 °CFever (infant)
38.5 °CFever (>3 months)
Respiratory Rate (tachypnoea)
Neonate (0–2 months)≥60 breaths/min
2–12 months≥50 breaths/min
1–5 years≥40 breaths/min
>5 years≥30 breaths/min
Blood Pressure (mmHg)
Term65/45
1 year75/50
4 years85/60
8 years95/65
10 years100/70
Head Circumference
Term35 cm ± 2
1 year+1 cm/month
2–3 years+2 cm/year
4–5 years+1 cm/year
5 years~53 cm
10 years56–57 cm
Height
Term52–55 cm
1 year75 cm
2–12 years6a + 77 cm
Weight Formulas
3–12 months(a + 9)/2 kg
1–6 years2a + 8 kg
>6 years(7a − 5)/2 kg
Developmental Milestones
Social smile1.5 months
Head control4 months
Sits unsupported7 months
Crawls10 months
Stands unsupported10–12 months
Walks12–13 months
Talks18 months
MUAC (6 months–5 years)
Obese>17.5 cm
Normal13.5–17.4 cm
At risk12.5–13.4 cm
Moderate malnutrition11.5–12.4 cm
Severe malnutrition<11.5 cm
Blood Transfusion
Whole blood20 mL/kg
pRBC10 mL/kg
Formula6 × (weight in kg) × Hb deficit
Normal Paediatric Lab Values
Haemoglobin (g/dL)Hematocrit (%)
Term newborn: 13–2040–58
1 month: 11–1832–54
2 months: 10–1528–44
1–2 years: 10–1332–40
>2 years: 11–1433–42
CSF WBC (/mm³)
Term newborn0–25
>2 weeks0–5

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