Myocarditis

Myocarditis is inflammation of the myocardium. Inflammation may cause severe, acute heart failure, which may require organ support or an emergency heart transplant in fulminant cases. The majority of cases are caused by viruses. It often occurs with pericarditis (myopericarditis).…

Syncope

Syncope is a transient loss of consciousness due to global cerebral hypoperfusion that occurs with rapid onset, short duration, and spontaneous complete recovery. This definition excludes other causes of loss of consciousness, such as epilepsy. Reflex syncope is the most…

Hypertrophic Cardiomyopathy (HCM)

Hypertrophic cardiomyopathy is characterised by hypertrophy of cardiomyocytes, resulting in thickened ventricular walls and reduced volume of the lumen. It may lead to heart failure with preserved ejection fraction, since the heart can contract properly, but its ability to relax…

Hypertrophic Obstructive Cardiomyopathy (HOCM)

Hypertrophic obstructive cardiomyopathy is characterised by left ventricular outflow tract obstruction, myocardial hypertrophy, and diastolic dysfunction. It is commonly caused by genetic mutations in sarcomere proteins. There is a hypertrophied interventricular septum, which blocks blood from flowing through the aortic…

Cardiomyopathies

Cardiomyopathies are disease processes that affect the myocardium – the contractile portion of the heart. They are characterized by impaired filling and contractility of the heart, which leads to increased pulmonary hydrostatic pressure and congestive heart failure symptoms. There may…