Dizziness and Vertigo

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Last updated: April 20, 2026Bookmark

Dizziness is a sensation that produces spatial disorientation.

Vertigo is a sensation of movement. It is usually perceived as a spinning sensation. Its cause is mainly neurological in origin, unlike presyncope – a feeling of light-headedness or faintness – whose cause is primarily cardiovascular.

Vertigo is often accompanied by nystagmus

Definition of terms

Terms usedDefinition
VertigoA sensation of movement. It can be rotational, linear, or tilting, such as “spinning”, “whirling”, or “turning”. It can be the movement of the patient or of their surroundings
DisequilibriumSensation of instability of body position while walking or standing. Described as being “off-balance.”
OscillopsiaBlurred vision and inability to focus on objects with motion. For example, the individual cannot read a sign while walking. It is seen with loss of the vestibulo-ocular reflex in bilateral or central vestibular dysfunction.
LightheadednessSense of impending faint or presyncope
Physiologic dizzinessCan be caused by motion sickness or height-related vertigo

Types of dizziness

DizzinessSome causes
Physiologic dizzinessMotion sickness and height-related vertigo
Multi-sensory dizzinessDiabetes and aging, which result in partial loss of multiple sensory systems

Characteristics of vertigo and some causes

CharacteristicExamples
Single, prolonged episode of vertigoVestibular neuronitis, labyrinthine damage, lateral medullary (Wallenberg’s syndrome), and cerebellar infarction
Recurrent episodes of vertigoMeniere’s disease, vertebrobasilar insufficiency, migraine, and perilymphatic fistula
Positional vertigoBenign positional paroxysmal vertigo (BPPV)
Other causes of vertigoOsteosclerosis, acoustic neuroma, cerebellopontine angle tumors, multiple sclerosis, Ramsay-Hunt syndrome, disequilibrium syndrome, anxiety, and drugs

Classification of Vertigo

TypeDescription
Peripheral VertigoInvolves vestibular organs and the vestibular nerve (first-order neurons)
Central VertigoInvolves the brainstem and the central nervous System
Ocular VertigoCaused by a mismatch of information received from the eyes with the vestibular system and somatosensory system
Psychogenic VertigoOccurs in patients suffering from emotional tension and anxiety

Central vs Peripheral Vertigo

Peripheral vertigoCentral vertigo
IntensitySevereMild
DurationEpisodicLasts longer
FatigabilityFatigues, adaptationDoes not fatigue
Associated symptomsNausea/vomiting, hearing loss, sweating, tinnitusWeakness, numbness, falls, diplopia, dysarthria, dysphagia, ataxia (cerebellar infarct)
Eye closureSymptoms are worse with eyes closedSymptoms better with eyes closed
NystagmusHorizontal, may be unilateral, rotaryVertical, bilateral
Ocular (gaze) fixationSuppresses nystagmus (may not suppress during the acute phase)No effect or enhances nystagmus
CausesBenign Paroxysmal Positional Vertigo (BPPV, 50%), Vestibular neuritis, Labyrinthitis, Meniere’s disease, foreign body in ear canal, perilymphatic fistula, Aminoglycosides (vestibulotoxic), head trauma, congenital syphilis, acoustic neuroma, Cerebellopontine angle tumor, multiple sclerosisVertebrobasilar insufficiency, Wallenberg syndrome, Basilar migraine, Cerebellar infarction, Brainstem tumor, Epilepsy, Posterior circulation insufficiency, Ramsay-Hunt syndrome
  • Patient History
    • Describe the dizziness: first, establish that the patient is experiencing vertigo and NOT pre-syncope: the patient may report that they or their surroundings feel like they are spinning or swaying while stationary in vertigo.
    • Chronicity: how long has it been going on, and how long does it last? Episodic or constant? Acute or recurrent?
    • Does the feeling change with any particular action? A change in position? Provoking factors – Head position, head injury, recent URTI, “pop” sensation or changes in ear pressure, headache
    • Hearing loss? (most likely peripheral vertigo)
    • Other symptoms include nausea, vomiting, and focal neurological defects such as diplopia, dysarthria, numbness, and weakness.
    • Medications in current and past use: salicylates, aminoglycosides, glycopeptides (vancomycin), loop diuretics, antimalarials (chloroquine, quinine), cytotoxic drugs.
    • History of trauma
    • History of ear surgery
    • How symptoms affect daily living (at home and occupational)
    • Rule out stroke (Wallenberg’s syndrome, cerebellar infarct) and SOLs, particularly in older patients. Risk factors of stroke (age > 65 years, HTN, DM), hemisthesia, dysphagia, Cranial nerve palsy, symptoms of raised ICP: headache, vomiting, papilledema, diplopia, bradycardia, Hypertension, irregular breathing, altered mental status, papilledema on ocular exam. NB: It is important to do a Non-contrast CT in such patients
  • Signs and symptoms of central vertigo
    • Lasts longer (with the major exception of infarcts)
    • Diplopia
    • Dysarthria
    • Dysphagia (especially brainstem lesions)
    • Ataxia
    • Vertical nystagmus (more notable with gaze fixation)
    • No hearing loss or tinnitus
  • Signs and symptoms of peripheral vertigo
    • Tends to be episodic
    • Tinnitus
    • Hearing loss
    • Severe nausea and vomiting
    • Horizontal nystagmus (lessens with gaze fixation)
  • Physical examination
    • Vital signs for orthostatic hypotension
    • Assess for nystagmus
    • Romberg test
      • The patient stands with feet at shoulder-width apart, and after a minute, is asked to close their eyes.
      • Loss of balance → Positive Romberg test → vertigo
    • Caloric stimulation test
      • Tests the health of the vestibular nerve
      • Normal ear (COWS- cold opposite, warm same): Cold water nystagmus, fast beat towards the opposite ear. Warm water nystagmus fast beat towards the same ear
      • Vestibular nerve damage: Abnormal nystagmus
    • Dix-Hallpike maneuver
      • Gold standard test for diagnosing benign paroxysmal positional vertigo (BPPV)
      • The patient is seated upright examination bed with their legs outstretched.
      • Rotate the head 45 degrees in one direction (you must do both sides). Observe for nystagmus for about 30 seconds.
      • Lower the patient down to a supine position with their head hanging over the bed (about 30 degrees below the horizontal plane)
      • Observe for nystagmus for at least 30 seconds.
      • A positive test is the presence of nystagmus.
      • Contraindications include cervical instability, acute neck trauma, cervical disc prolapse, high-grade carotid stenosis, and vertebrobasilar disease.
    • Other tests
      • HINTS test (head impulse, nystagmus, and test for skew)
      • Tandem walking
      • Electronystagmography (ENG)/Videonystagmography (VNG) battery
  • Investigations
    • Complete blood count to look for infection and anaemia
    • Random blood sugar
      • Hyperglycaemia is a systemic cause of vertigo
    • Toxicology panel for any vestibulotoxic drugs
Reference Intervals
Biochemistry
ACTHP: <80 ng/L
ALTP: 5–35 U/L
AlbuminP: 35–50 g/L
AldosteroneP: 100–500 pmol/L
Alk. phosphataseP: 30–130 U/L
α-AmylaseP: 0–180 IU/dL
α-FetoproteinS: <10 kU/L
Angiotensin IIP: 5–35 pmol/L
ADHP: 0.9–4.6 pmol/L
ASTP: 5–35 U/L
BicarbonateP: 24–30 mmol/L
BilirubinP: 3–17 μmol/L
BNPP: <50 ng/L
CRPP: <10 mg/L
CalcitoninP: <0.1 mcg/L
Calcium (ionized)P: 1.0–1.25 mmol/L
Calcium (total)P: 2.12–2.60 mmol/L
ChlorideP: 95–105 mmol/L
CholesterolP: <5.0 mmol/L
VLDLP: 0.128–0.645 mmol/L
LDLP: <2.0 mmol/L
HDLP: 0.9–1.93 mmol/L
Cortisol AMP: 450–700 nmol/L
Cortisol MidnightP: 80–280 nmol/L
CK ♂P: 25–195 U/L
CK ♀P: 25–170 U/L
CreatinineP: 70–100 μmol/L
FerritinP: 12–200 mcg/L
FolateS: 2.1 mcg/L
FSHP: 2–8 U/L ♂; >25 menopause
GGT ♂P: 11–51 U/L
GGT ♀P: 7–33 U/L
Glucose (fasting)P: 3.5–5.5 mmol/L
Growth hormoneP: <20 mu/L
HbA1C (DCCT)B: 4–6%
HbA1C (IFCC)B: 20–42 mmol/mol
Iron ♂S: 14–31 μmol/L
Iron ♀S: 11–30 μmol/L
Lactate (venous)P: 0.6–2.4 mmol/L
Lactate (arterial)P: 0.6–1.8 mmol/L
LDHP: 70–250 U/L
LHP: 3–16 U/L
MagnesiumP: 0.75–1.05 mmol/L
OsmolalityP: 278–305 mosmol/kg
PTHP: 0.8–8.5 pmol/L
PotassiumP: 3.5–5.3 mmol/L
Prolactin ♂P: <450 U/L
Prolactin ♀P: <600 U/L
PSAP: 0–4 mcg/mL
Protein (total)P: 60–80 g/L
Red cell folateB: 0.36–1.44 μmol/L
Renin (erect)P: 2.8–4.5 pmol/mL/h
Renin (recumbent)P: 1.1–2.7 pmol/mL/h
SodiumP: 135–145 mmol/L
TBGP: 7–17 mg/L
TSHP: 0.5–4.2 mU/L
T4P: 70–140 nmol/L
Free T4P: 9–22 pmol/L
TIBCS: 54–75 μmol/L
TriglyceridesP: 0.50–2.3 mmol/L
T3P: 1.2–3.0 nmol/L
Troponin TP: <0.1 mcg/L
Urate ♂P: 210–480 μmol/L
Urate ♀P: 150–390 μmol/L
UreaP: 2.5–6.7 mmol/L
Vitamin B12S: 0.13–0.68 nmol/L
Vitamin DS: 50 nmol/L
Arterial Blood Gases
pH7.35–7.45
PaCO₂4.7–6.0 kPa
PaO₂>10.6 kPa
Base excess±2 mmol/L
Urine
Cortisol (free)<280 nmol/24h
Hydroxyindole acetic acid16–73 μmol/24h
Hydroxymethylmandelic acid16–48 μmol/24h
Metanephrines0.03–0.69 μmol/mmol cr.
Osmolality350–1000 mosmol/kg
17-Oxogenic steroids ♂28–30 μmol/24h
17-Oxogenic steroids ♀21–66 μmol/24h
17-Oxosteroids ♂17–76 μmol/24h
17-Oxosteroids ♀14–59 μmol/24h
Phosphate (inorganic)15–50 mmol/24h
Potassium14–120 mmol/24h
Protein<150 mg/24h
Protein/creatinine ratio<3 mg/mmol
Sodium100–250 mmol/24h
Haematology
WCC4.0–11.0 ×10⁹/L
RBC ♂4.5–6.5 ×10¹²/L
RBC ♀3.9–5.6 ×10¹²/L
Hb ♂130–180 g/L
Hb ♀115–160 g/L
PCV ♂0.4–0.54 L/L
PCV ♀0.37–0.47 L/L
MCV76–96 fL
MCH27–32 pg
MCHC300–360 g/L
RDW11.6–14.6%
Neutrophils2.0–7.5 ×10⁹/L (40–75%)
Lymphocytes1.0–4.5 ×10⁹/L (20–45%)
Eosinophils0.04–0.44 ×10⁹/L (1–6%)
Basophils0–0.10 ×10⁹/L (0–1%)
Monocytes0.2–0.8 ×10⁹/L (2–10%)
Platelets150–400 ×10⁹/L
Reticulocytes0.8–2.0% / 25–100 ×10⁹/L
Prothrombin time10–14 s
APTT35–45 s
Paediatric
Pulse Rate (bpm)
Neonate140–160
Infant <1yr120–140
1–5 years110–130
5–12 years80–120
>12 years70–100
Respiratory Rate (tachypnoea)
0–2 months≥60/min
2–12 months≥50/min
1–5 years≥40/min
>5 years≥30/min
Blood Pressure (mmHg)
Term65/45
1 year75/50
4 years85/60
8 years95/65
10 years100/70
Weight Formulas
3–12 months(a + 9)/2 kg
1–6 years2a + 8 kg
>6 years(7a − 5)/2 kg
Haemoglobin (g/dL)
Term newborn13–20
1 month11–18
2 months10–15
1–2 years10–13
>2 years11–14
MUAC (6 months–5 years)
Obese>17.5 cm
Normal13.5–17.4 cm
At risk12.5–13.4 cm
Moderate malnutrition11.5–12.4 cm
Severe malnutrition<11.5 cm
Developmental Milestones
Social smile1.5 months
Head control4 months
Sits unsupported7 months
Crawls10 months
Stands unsupported10–12 months
Walks12–13 months
Talks18 months
CSF WBC (/mm³)
Term newborn0–25
>2 weeks0–5
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