TOTW #8 - Haematology 25 challenging trivia questions on Haematology Start QuizPage 1 of 25 Which one of the following statements is false? Extravascular haemolysis occurs in hemolytic disease of the newborn Intravascular hemolysis is generally complement mediated Extravascular hemolysis occurs in the spleen or liver Extravascular hemolysis is always pathological Page 2 of 25 On what chromosome is the sickle cell gene point mutation? Chromosome 7 Chromosome 13 Chromosome 11 Chromosome 5 Page 3 of 25 Which of the following viruses is the common cause of sickle cell aplastic crisis? Parvovirus B19 Coxsackievirus Epstein-Barr virus Varicella zoster virus Page 4 of 25 Which one of the following will not result in microcytic hypochromic anemia? Iron deficiency anemia Acute blood loss Lead poisoning Sideroblastic anemia Page 5 of 25 Select the false statement regarding factors affecting rate of iron absorption Acids increase iron absorption Inflammation increases iron absorption Tannates e.g. tea decrease iron absorption Reduced serum hepcidin increases iron absorption Page 6 of 25 A clinical feature commonly seen in Von Willebrand disease is? Menorrhagia Carvenous thrombosis Hemothorax Intraventricular hemorrhage Page 7 of 25 Which of the following is NOT true about Hodgkin’s lymphoma? Bone marrow is involved in Stage 4 Reed Sternberg cells are characteristic Staging is done by blood tests Cervical lymphadenopathy is common Page 8 of 25 The specimen for coagulation testing is? Platelet-poor plasma from citrated blood Platelet-rich plasma from citrated blood Washed red blood cells Heparin anti-coagulated whole blood Page 9 of 25 CD20 is a phosphoprotein generally expressed in? . T-cells B cells and B-cell lymphoma Plasma cells Natural killer cells Page 10 of 25 The most common subtype of Non-Hodgkin lymphoma in African children is? Follicular lymphoma Burkitt lymphoma Mantle cell lymphoma Diffuse large B-cell lymphoma Page 11 of 25 A microscopic picture is shown below. What is the diagnosis? Langerhan cells Giant cells Megaloblastosis Emperipolesis Page 12 of 25 Pappenheimer bodies are composed of? Copper Iron Zinc Manganese Page 13 of 25 Ineffective erythropoiesis is characteristic of which one: B-Thalassemia major Iron deficiency anemia Aplastic anemia Sickle cell anemia Page 14 of 25 Which of the following is a poor prognostic indicator in acute lymphoblastic leukemia (ALL) t(4;11)(q21;23) t(1;19)(q23;p13) t(5;14)(q(31.1;q32.1) t(12;21)(p13.2,q22.1) Page 15 of 25 A 70-year-old male patient presents with bone pain in the back and renal failure. Bone marrow aspirate shows abnormal blasts. Which finding is expected in the RBCs of the peripheral smear? Rouleaux formation Schistocytes Teardrop-shaped RBCs Dacrocytes Page 16 of 25 Which one of the following stains may be used to characterise bone marrow fibrosis? Period Acid Schiff Masson Trichome Prussian Blue Hematoxylin and eosin Page 17 of 25 Starry sky appearance is seen in Hodgkins lymphoma Burkitts lymphoma Follicular lymphoma Small lymphocytic lymphoma Page 18 of 25 Which of the following is an established risk factor for Acute myeloid leukemia? Allergies Caffeine consumption Male sex Vaccination Page 19 of 25 Which of the following is not true regarding the Reed-Sternberg cell? It is multi-nucleated Of B cell lineage Characteristic of Non-Hodgkin’s lymphoma Expresses CD15 and CD30 Page 20 of 25 Romanowsky stains are used universally for routine staining of blood films. Which of the following is not among them? May-Grunwald stain Jenner’s stain Carbol fuchsin stain Giemsa’s stain Page 21 of 25 Which of the following is not a vitamin K dependent factor VII IX XI X Page 22 of 25 Warfarin mediates anticoagulation by binding and preventing conversion of prothrombin antagonizing vit K chelating calcium augmenting fibrinolysis Page 23 of 25 Which of the following is CD15 and CD30 negative variant Hodgkin Lymphoma nodular sclerosis nodular lymphocyte predominant lymphocyte depleted mixed cellularity Page 24 of 25 PML-RARA fusion gene is associated with APL AML ALL CLL Page 25 of 25 Which of the following cells is diagnostic for Hodgkin Lymphoma Smudge cell Aschoff bodies Reed Sternberg cells Mott cells Multiple Authors | WebsiteTOTW #26 - MicrobiologyTOTW #25 - PsychiatryTOTW #24 - BiochemistryTOTW #23 - Haematology Previous Post TOTW #7 - Paediatrics Next Post How to Plan Your Week