Muscle Tissue
Illustrate the ultrastructural arrangement of contractile fibres in striated muscle What are the structural components of intercalated discs in cardiac muscle Distinguish between a diad and a triad in striated muscle Diad Triad Definition T-tubule and 1 terminal cisterna of…
Bone Tissue
Distinguish between endochondral and membranous ossification. Give examples Endochondral ossification Intramembranous ossification Definition Development of bone tissue within cartilage Development of bone tissue within mesenchymal tissue without cartilage formation Mechanism Cartilage is formed first and bone is laid on it…
Connective Tissue
Distinguish between resident and non-resident connective tissue cells and give examples in each class Resident cells Non-resident cells Characteristics Stable – exhibit little movement and stay permanently in the tissue These cells have migrated into the tissue from blood in…
Epithelial Tissue
The Cell
As regards membranous proteins, distinguish between carrier proteins, channel proteins, and pumps Carrier proteins Channels Pumps Function Binds specific molecules and changes their conformation to transport them across the cell membrane Allows passive diffusion of ions, small molecules and water…
Methods in Histology
Plasma Cell Dyscrasias
Plasma cell dyscrasias involve the abnormal proliferation of plasma cells. These B-cell clones synthesize and secrete a single monoclonal immunoglobulin or its fragments, e.g., free light chains and free heavy chains. These monoclonal immunoglobulins are termed M proteins and appear…
Lymphoma
Overview Lymphomas are tumours arising from lymphoid cells. They have a much less dramatic presentation than leukaemias, and are classified into 2 major groups – Hodgkin’s lymphoma and Non-Hodgkin’s lymphoma – based on morphology and immunophenotype. Definition of terms Term…
Myelodysplastic Syndromes
Myelodysplastic syndromes are a group of disorders that are characterised by dysplastic and ineffective haematopoiesis. This leads to abnormal growth of pluripotent stem cells in the bone marrow, causing deficiencies affecting several cell lines. It is sometimes referred to as…