Muscle Tissue
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Dr. Jeffrey Kalei
Author and illustrator for Hyperexcision. Interested in emergency room medicine. I have a passion for medical education and drawing.
Bone Tissue
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Connective Tissue
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Epithelial Tissue
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The Cell
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Methods in Histology
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Plasma Cell Dyscrasias
Overview Plasma cell disorders involve the abnormal proliferation of plasma cells. These B-cell clones synthesize and secrete a single monoclonal immunoglobulin or its fragments e.g. free light chains, and free heavy chains. These monoclonal immunoglobulins are termed M proteins and…
Lymphomas
Overview Lymphomas are tumors arising from lymphoid cells. They have a much less dramatic presentation than leukemias. They are classified into 2 major groups – Hodgkin’s and Non-Hodgkin’s – based on morphology and immunophenotype. 2/3 of lymphoma present with Lymphadenopathy.…
Myelodysplastic Syndromes
Myelodysplastic syndromes are characterized by dysplastic and ineffective hematopoiesis – bone marrow failure**.** It is sometimes described as “pre-leukemic” since there is a risk of transformation into acute leukemia (30%). In MDS, there is varied anemia, thrombocytopenia, and leukopenia. Hence…
Myeloproliferative Neoplasms
Overview Myeloproliferative neoplasms are abnormal proliferations of one or more terminal myeloid cell lines in the peripheral blood (RBCs, WBCs, platelets). Myeloproliferative neoplasms are poorly characterized and poorly undersood. They all cause a predilection to extramedullary hematopoiesis, myelofibrosis, and transformation…