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Last updated: June 26, 2026Bookmark

Atelectasis is the partial or complete collapse of a lung due to deflation of air in the alveoli.

Types of atelectasis

TypeDescription
Obstructive atelectasisDue to blockage within the airways. It is also known as absorptive atelectasis.
Non-obstructive atelectasisDue to pressure from outside the lungs
Adhesive atelectasisDue to decreased surfactant levels
Rounded atelectasis (Blesovsky or folded lung syndrome)Due to pleural disease, e.g., asbestosis. The thickened pleura causes lung tissue to invaginate
Post-operative atelectasisDue to shallow breathing patterns after thoracic or abdominal surgery. It commonly occurs 72 hours after surgery. The mechanism is a combination of obstruction and compression.
Cicatriziation atelectasisDue to lung fibrosis or scarring
Relaxation atelectasisThis occurs when the lung loses contact with the chest wall, e.g., pneumothorax
Replacement atelectasisThis occurs when the alveoli are replaced by tumour tissue
Middle lobe syndromeThis is recurrent collapse of the right middle lobe or lingula
  • Causes
    • Postoperative atelectasis
      • General anaesthesia
      • Pain which limits deep breathing and coughing
      • Muscle relaxants which reduce lung volumes
    • Obstructive atelectasis
      • Endobronchial tumors
      • Mucus plugs in COPD and asthma
      • Foreign body aspiration
    • Non-obstructive atelectasis
    • Adhesive atelectasis
      • Plumonary contusion
      • Pneumonia
      • Aging
      • Neonatal distress syndrome
  • Risk factors
    • Surgery
      • Thoracic surgery
      • Cardiac surgery
      • Upper abdominal surgery
    • Peri-operative risk factors
      • General anaesthesia (90%)
      • Muscle relaxants
      • High FiO2
      • Poor pain control
      • Opioids
      • Mechanical ventilation
    • Obesity
    • Pregnancy
    • Prolonged immobilisation
  • Pathophysiology
    • Basilar segments are more likely to collapse in supine patients
    • Airway obstruction → absorption of air distal to the obstruction → decreased alveolar volume → collapse
    • External compression → increased intrathoracic pressure prevents alveoli from expanding during inspiration
    • Loss of surfactant → increased surface tension → alveolar collapse
    • Epithelial injury and apoptosis → fluid leakage into alveolar spaces
  • Signs and Symptoms
    • Mild fever
    • Crackles on auscultation
    • Reduced breath sounds
    • Cyanosis in severe cases
    • Mediastinal shift towards the affected side
    • Dullness on percussion
    • Pleuritic chest pain
    • Cough
    • Tachypnoea
  • Investigations
    • Chest X-ray
      • Linear poacitis
      • Loss of lung volume
      • Elevated hemidiaphragm
      • Tracheal shift towards the affected side
      • Fissure displacement
      • Pulmonary opacity
    • CT scan of the chest is more sensitive than chest X-ray
      • Loss of lung volume
      • Dependent lung colapse
    • Bronchoscopy for mucus plug, foreign body and endobronchial tumors. It can be diagnostic and therapeutic.
    • Arterial blood gas (ABG) analysis
  • Treatment
    • Oxygen if indicated
    • Lung re-expansion strategies
      • Incentive spirometry
      • Chest physiotherapy
      • Acapella device
      • Early ambulation or mobilisation
      • Upright positioning
    • Positive pressure ventilation when indicated
    • Tracheal suction or bronchoscopy to clear the airway
    • Mucolytics may help in specific cases
Reference Intervals ›
Biochemistry
ACTHP: <80 ng/L
ALTP: 5–35 U/L
AlbuminP: 35–50 g/L
AldosteroneP: 100–500 pmol/L
Alk. phosphataseP: 30–130 U/L
α-AmylaseP: 0–180 IU/dL
α-FetoproteinS: <10 kU/L
Angiotensin IIP: 5–35 pmol/L
ADHP: 0.9–4.6 pmol/L
ASTP: 5–35 U/L
BicarbonateP: 24–30 mmol/L
BilirubinP: 3–17 μmol/L
BNPP: <50 ng/L
CRPP: <10 mg/L
CalcitoninP: <0.1 mcg/L
Calcium (ionized)P: 1.0–1.25 mmol/L
Calcium (total)P: 2.12–2.60 mmol/L
ChlorideP: 95–105 mmol/L
CholesterolP: <5.0 mmol/L
VLDLP: 0.128–0.645 mmol/L
LDLP: <2.0 mmol/L
HDLP: 0.9–1.93 mmol/L
Cortisol AMP: 450–700 nmol/L
Cortisol MidnightP: 80–280 nmol/L
CK ♂P: 25–195 U/L
CK ♀P: 25–170 U/L
CreatinineP: 70–100 μmol/L
FerritinP: 12–200 mcg/L
FolateS: 2.1 mcg/L
FSHP: 2–8 U/L ♂; >25 menopause
GGT ♂P: 11–51 U/L
GGT ♀P: 7–33 U/L
Glucose (fasting)P: 3.5–5.5 mmol/L
Growth hormoneP: <20 mu/L
HbA1C (DCCT)B: 4–6%
HbA1C (IFCC)B: 20–42 mmol/mol
Iron ♂S: 14–31 μmol/L
Iron ♀S: 11–30 μmol/L
Lactate (venous)P: 0.6–2.4 mmol/L
Lactate (arterial)P: 0.6–1.8 mmol/L
LDHP: 70–250 U/L
LHP: 3–16 U/L
MagnesiumP: 0.75–1.05 mmol/L
OsmolalityP: 278–305 mosmol/kg
PTHP: 0.8–8.5 pmol/L
PotassiumP: 3.5–5.3 mmol/L
Prolactin ♂P: <450 U/L
Prolactin ♀P: <600 U/L
PSAP: 0–4 mcg/mL
Protein (total)P: 60–80 g/L
Red cell folateB: 0.36–1.44 μmol/L
Renin (erect)P: 2.8–4.5 pmol/mL/h
Renin (recumbent)P: 1.1–2.7 pmol/mL/h
SodiumP: 135–145 mmol/L
TBGP: 7–17 mg/L
TSHP: 0.5–4.2 mU/L
T4P: 70–140 nmol/L
Free T4P: 9–22 pmol/L
TIBCS: 54–75 μmol/L
TriglyceridesP: 0.50–2.3 mmol/L
T3P: 1.2–3.0 nmol/L
Troponin TP: <0.1 mcg/L
Urate ♂P: 210–480 μmol/L
Urate ♀P: 150–390 μmol/L
UreaP: 2.5–6.7 mmol/L
Vitamin B12S: 0.13–0.68 nmol/L
Vitamin DS: 50 nmol/L
Arterial Blood Gases
pH7.35–7.45
PaCO₂4.7–6.0 kPa
PaO₂>10.6 kPa
Base excess±2 mmol/L
Urine
Cortisol (free)<280 nmol/24h
Hydroxyindole acetic acid16–73 μmol/24h
Hydroxymethylmandelic acid16–48 μmol/24h
Metanephrines0.03–0.69 μmol/mmol cr.
Osmolality350–1000 mosmol/kg
17-Oxogenic steroids ♂28–30 μmol/24h
17-Oxogenic steroids ♀21–66 μmol/24h
17-Oxosteroids ♂17–76 μmol/24h
17-Oxosteroids ♀14–59 μmol/24h
Phosphate (inorganic)15–50 mmol/24h
Potassium14–120 mmol/24h
Protein<150 mg/24h
Protein/creatinine ratio<3 mg/mmol
Sodium100–250 mmol/24h
Haematology
WCC4.0–11.0 ×10⁹/L
RBC ♂4.5–6.5 ×10¹²/L
RBC ♀3.9–5.6 ×10¹²/L
Hb ♂130–180 g/L
Hb ♀115–160 g/L
PCV ♂0.4–0.54 L/L
PCV ♀0.37–0.47 L/L
MCV76–96 fL
MCH27–32 pg
MCHC300–360 g/L
RDW11.6–14.6%
Neutrophils2.0–7.5 ×10⁹/L (40–75%)
Lymphocytes1.0–4.5 ×10⁹/L (20–45%)
Eosinophils0.04–0.44 ×10⁹/L (1–6%)
Basophils0–0.10 ×10⁹/L (0–1%)
Monocytes0.2–0.8 ×10⁹/L (2–10%)
Platelets150–400 ×10⁹/L
Reticulocytes0.8–2.0% / 25–100 ×10⁹/L
Prothrombin time10–14 s
APTT35–45 s
Paediatric
Pulse Rate (bpm)
Neonate140–160
Infant <1yr120–140
1–5 years110–130
5–12 years80–120
>12 years70–100
Respiratory Rate (tachypnoea)
0–2 months≥60/min
2–12 months≥50/min
1–5 years≥40/min
>5 years≥30/min
Blood Pressure (mmHg)
Term65/45
1 year75/50
4 years85/60
8 years95/65
10 years100/70
Weight Formulas
3–12 months(a + 9)/2 kg
1–6 years2a + 8 kg
>6 years(7a − 5)/2 kg
Haemoglobin (g/dL)
Term newborn13–20
1 month11–18
2 months10–15
1–2 years10–13
>2 years11–14
MUAC (6 months–5 years)
Obese>17.5 cm
Normal13.5–17.4 cm
At risk12.5–13.4 cm
Moderate malnutrition11.5–12.4 cm
Severe malnutrition<11.5 cm
Developmental Milestones
Social smile1.5 months
Head control4 months
Sits unsupported7 months
Crawls10 months
Stands unsupported10–12 months
Walks12–13 months
Talks18 months
CSF WBC (/mm³)
Term newborn0–25
>2 weeks0–5
Calculator ›

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