A 32-year-old with knee pain and inability to bear weight following road traffic accident

Last updated: April 7, 2026Bookmark

A 32-year-old man is brought to the emergency department after a motorbike accident. He reports severe pain in the left knee and inability to bear weight. On inspection, there is gross swelling and deformity of the knee joint. The leg appears shortened and displaced laterally. He is in severe distress. Distal pulses in the dorsalis pedis and posterior tibial arteries are absent. The foot is pale and cool to the touch. Sensation over the dorsum of the foot is reduced, and he is unable to dorsiflex the ankle.

Q1. What is the most likely diagnosis?

Posterior knee dislocation with neurovascular injury

Knee dislocation is a true orthopaedic EMERGENCY

It occurs when there is rupture of at least two of the four major knee ligament structures. They can be due to a high-energy mechanism (50%), a sports injury (33%), or a low-energy mechanism (such as a fall).

Dislocations due to high-energy mechanisms have a higher risk of vascular injury

Q2. Classify knee dislocations (based on the direction of displacement of the tibia)
ClassificationDescription
Anterior dislocation (40%)Direct blow to the proximal tibia (dashboard injury). High risk of vascular injury due to disruption of the popliteal artery
Posterior dislocationDirect blow to the proximal tibia (dashboard injury). High risk of vascular injury due to disruption of the popliteal artery
Medial dislocationRare and usually irreducible. The PCL remains intact as the tibia rotates around the femur. It presents with a dimple on the medial side. Associated with the “dimple” sign.
Lateral dislocationDue to a varus force
Posterolateral (Rotatory) dislocationRare and usually irreducible. The PCL remains intact as the tibia rotates around the femur. It presents with a dimple on the medial side. Associated with the “dimple” sign.
Types of Knee Dislocation
Q3. What are the typical physical exam findings in a knee dislocation?

Overweight or obese (risk factor)

Hyperextension of the knee

Deformity

Knee swelling

Popliteal ecchymosis

Dimple sign (rotatory dislocation, may be irreducible)

Neurovascular examination

Capillary refill, skin color, and temperature

Distal pulses (dorsalis pedis and posterior tibial)

Ankle-brachial index (ABI)

Foot drop (L5 – common peroneal nerve injury)

Q4. What are the hard signs of limb ischaemia?

Absent pulse

Bleeding

Expanding hematoma

Cold cyanotic foot

Require urgent surgery for exploration (vascular surgery)

Soft signs include weak pulse, prolonged capillary refill, colour or temperature changes

Q5. What is included in the acute management of a knee dislocation?

Resuscitation

Consent for closed reduction

Analgesia and sedation

Pre-reduction neurovascular examination

Closed reduction

Post-reduction neurovascular examination and ankle brachial index

Plaster immobilization or external fixator (if unstable or vascular repair needed)

Non-weight bearing with crutches

Rotatory dislocation requires open reduction via an anteromedial approach after neurovascular examination

A temporary external fixator is used for unstable patients, persistent subluxation, or severe soft tissue injury

If there is a fracture dislocation, reduce the fracture, then a post-reduction CT scan is obtained. MRI is ordered too, before definitive repair.

Q6. What are the possible post-reduction ankle-brachial index (ABI)/neurovascular exam findings following closed reduction of a knee dislocation?
ABI and neurovascular examIntervention
> 0.9Observation with serial neurovascular examinations over 24 – 48 hours
< 0.9 with asymmetric pulsesCT angiography or arteriography to evaluate the blood vessels
Absent pulses or clear hard signs of ischaemiaEmergency surgical exploration (vascular surgery). If ischaemia > 6 hours → urgent revascularization +/- fasciotomy

Reference Intervals
Biochemistry
ACTHP: <80 ng/L
ALTP: 5–35 U/L
AlbuminP: 35–50 g/L
AldosteroneP: 100–500 pmol/L
Alk. phosphataseP: 30–130 U/L
α-AmylaseP: 0–180 IU/dL
α-FetoproteinS: <10 kU/L
Angiotensin IIP: 5–35 pmol/L
ADHP: 0.9–4.6 pmol/L
ASTP: 5–35 U/L
BicarbonateP: 24–30 mmol/L
BilirubinP: 3–17 μmol/L
BNPP: <50 ng/L
CRPP: <10 mg/L
CalcitoninP: <0.1 mcg/L
Calcium (ionized)P: 1.0–1.25 mmol/L
Calcium (total)P: 2.12–2.60 mmol/L
ChlorideP: 95–105 mmol/L
CholesterolP: <5.0 mmol/L
VLDLP: 0.128–0.645 mmol/L
LDLP: <2.0 mmol/L
HDLP: 0.9–1.93 mmol/L
Cortisol AMP: 450–700 nmol/L
Cortisol MidnightP: 80–280 nmol/L
CK ♂P: 25–195 U/L
CK ♀P: 25–170 U/L
CreatinineP: 70–100 μmol/L
FerritinP: 12–200 mcg/L
FolateS: 2.1 mcg/L
FSHP: 2–8 U/L ♂; >25 menopause
GGT ♂P: 11–51 U/L
GGT ♀P: 7–33 U/L
Glucose (fasting)P: 3.5–5.5 mmol/L
Growth hormoneP: <20 mu/L
HbA1C (DCCT)B: 4–6%
HbA1C (IFCC)B: 20–42 mmol/mol
Iron ♂S: 14–31 μmol/L
Iron ♀S: 11–30 μmol/L
Lactate (venous)P: 0.6–2.4 mmol/L
Lactate (arterial)P: 0.6–1.8 mmol/L
LDHP: 70–250 U/L
LHP: 3–16 U/L
MagnesiumP: 0.75–1.05 mmol/L
OsmolalityP: 278–305 mosmol/kg
PTHP: 0.8–8.5 pmol/L
PotassiumP: 3.5–5.3 mmol/L
Prolactin ♂P: <450 U/L
Prolactin ♀P: <600 U/L
PSAP: 0–4 mcg/mL
Protein (total)P: 60–80 g/L
Red cell folateB: 0.36–1.44 μmol/L
Renin (erect)P: 2.8–4.5 pmol/mL/h
Renin (recumbent)P: 1.1–2.7 pmol/mL/h
SodiumP: 135–145 mmol/L
TBGP: 7–17 mg/L
TSHP: 0.5–4.2 mU/L
T4P: 70–140 nmol/L
Free T4P: 9–22 pmol/L
TIBCS: 54–75 μmol/L
TriglyceridesP: 0.50–2.3 mmol/L
T3P: 1.2–3.0 nmol/L
Troponin TP: <0.1 mcg/L
Urate ♂P: 210–480 μmol/L
Urate ♀P: 150–390 μmol/L
UreaP: 2.5–6.7 mmol/L
Vitamin B12S: 0.13–0.68 nmol/L
Vitamin DS: 50 nmol/L
Arterial Blood Gases
pH7.35–7.45
PaCO₂4.7–6.0 kPa
PaO₂>10.6 kPa
Base excess±2 mmol/L
Urine
Cortisol (free)<280 nmol/24h
Hydroxyindole acetic acid16–73 μmol/24h
Hydroxymethylmandelic acid16–48 μmol/24h
Metanephrines0.03–0.69 μmol/mmol cr.
Osmolality350–1000 mosmol/kg
17-Oxogenic steroids ♂28–30 μmol/24h
17-Oxogenic steroids ♀21–66 μmol/24h
17-Oxosteroids ♂17–76 μmol/24h
17-Oxosteroids ♀14–59 μmol/24h
Phosphate (inorganic)15–50 mmol/24h
Potassium14–120 mmol/24h
Protein<150 mg/24h
Protein/creatinine ratio<3 mg/mmol
Sodium100–250 mmol/24h
Haematology
WCC4.0–11.0 ×10⁹/L
RBC ♂4.5–6.5 ×10¹²/L
RBC ♀3.9–5.6 ×10¹²/L
Hb ♂130–180 g/L
Hb ♀115–160 g/L
PCV ♂0.4–0.54 L/L
PCV ♀0.37–0.47 L/L
MCV76–96 fL
MCH27–32 pg
MCHC300–360 g/L
RDW11.6–14.6%
Neutrophils2.0–7.5 ×10⁹/L (40–75%)
Lymphocytes1.0–4.5 ×10⁹/L (20–45%)
Eosinophils0.04–0.44 ×10⁹/L (1–6%)
Basophils0–0.10 ×10⁹/L (0–1%)
Monocytes0.2–0.8 ×10⁹/L (2–10%)
Platelets150–400 ×10⁹/L
Reticulocytes0.8–2.0% / 25–100 ×10⁹/L
Prothrombin time10–14 s
APTT35–45 s
Paediatric
Pulse Rate (bpm)
Neonate140–160
Infant <1yr120–140
1–5 years110–130
5–12 years80–120
>12 years70–100
Respiratory Rate (tachypnoea)
0–2 months≥60/min
2–12 months≥50/min
1–5 years≥40/min
>5 years≥30/min
Blood Pressure (mmHg)
Term65/45
1 year75/50
4 years85/60
8 years95/65
10 years100/70
Weight Formulas
3–12 months(a + 9)/2 kg
1–6 years2a + 8 kg
>6 years(7a − 5)/2 kg
Haemoglobin (g/dL)
Term newborn13–20
1 month11–18
2 months10–15
1–2 years10–13
>2 years11–14
MUAC (6 months–5 years)
Obese>17.5 cm
Normal13.5–17.4 cm
At risk12.5–13.4 cm
Moderate malnutrition11.5–12.4 cm
Severe malnutrition<11.5 cm
Developmental Milestones
Social smile1.5 months
Head control4 months
Sits unsupported7 months
Crawls10 months
Stands unsupported10–12 months
Walks12–13 months
Talks18 months
CSF WBC (/mm³)
Term newborn0–25
>2 weeks0–5
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