Electrocardiogram (EKG) Basics

Last updated: April 12, 2026Bookmark

Overview

An electrocardiogram (ECG/EKG) is a graphical representation of the electrical activity of the heart. It is one of the most common investigations carried out in cardiovascular medicine.

Willem Einthoven developed and added onto previous work on electrical charges in the heart, building the EKG we know and use today. He won the Nobel Prize in Medicine in 1924.

  • Normal EKG values
    • Heart rate: 60–100 bpm
    • PR interval: 0.12–0.20 s (3–5 small squares)
    • QRS duration: <0.12 s (≤3 small squares)
    • QTc:
      • <440 ms (men)
      • <460 ms (women)

EKG wave summary

ComponentRepresents
P waveAtrial depolarization
PR intervalAV nodal delay
QRS complexVentricular depolarization
ST segmentEarly ventricular repolarization (should be isoelectric)
T waveVentricular repolarization
QT intervalTotal ventricular electrical activity

Electrical Pathway

To understand an EKG, you must map the electrical impulse to physical contraction.

  • Electrical system of the heart
    • SA node: Impulse is generated from the sinoatrial node (SA node)
    • Atrial depolarization: Depolarization spreads through gap junctions through atrial muscle fibers, causing the atrium to contract. This creates the P wave.
    • AV node delay: Depolarization reaches the atrioventricular node (AV node), where it is delayed to allow blood to fill the ventricles. This creates the PR interval.
    • Bundle of His: Electrical discharge travels rapidly from the AV node first through the bundle of His, then into the right and left bundle branches. The left bundle branch depolarizes first and then sends current to the right bundle branch. The left bundle branch divides into anterior and posterior fascicles.
    • Purkinje fibers: these fibers distribute impulses throughout the ventricular walls
    • Ventricular depolarization: This causes ventricular contraction. Depolarization of the ventricles creates the QRS complex
    • Ventricular repolarization: Ventricular repolarization creates the T wave.
  • Summary of electrical events and EKG correlation
    • SA node firing → start of P wave
    • Atrial contraction → P wave
    • AV node delay → PR interval
    • Ventricular depolarization → QRS complex
    • Ventricular contraction → occurs during QRS/ST
    • Ventricular repolarization → T wave

EKG Leads (Viewpoints of the heart)

The conventional EKG machine consists of 12 leads divided into two groups, i.e., limb leads and precordial leads. Lead refers to the electrical view of the heart. If an impulse moves towards a lead, it shows a positive deflection and vice versa.

Types of leads on an EKG

TypeDescription
Limb leadsView the heart in a frontal/coronal plane (from the sides or the feet)
Standard limb leadsIncludes lead I, II, and III. Bipolar leads (2 electrodes of opposite polarity) and a ground electrode that minimizes activity from the source. Gives 3 views of the heart
Augmented limb leadsIncludes AvR, AvL, AvF. Gives 3 more angles to look at the heart with the heart at the center (’negative electrode’)
Precordial leadsGives a horizontal view of the heart (from the front/left side to back)

Standard limb leads

LeadDescriptionView
Lead IRight arm (-) to left arm (+)Lateral view
Lead IIRight arm (-) to left leg (+)Inferior view
Lead IIILeft arm (-) to left leg (+)Inferior view from the right

Augmented limb leads

Augmented limb leadViewNota bene
aVRRight atriumThe only electrode that records a negative deflection
aVLLeft lateral view
aVFInferior surface

Precordial leads

Precordial leadPositive electrode placementView
V14 ICS to the right of the sternumSeptal
V24 ICS to the left of the sternumSeptal
V3Between V2 and V4Anterior
V45 ICS in left MCLAnterior
V5Level with V4 at the left anterior axillary lineLateral
V6Level with V5 at the left midaxillary lineLateral

EKG territories

LeadsTerritoryArtery
II, III, aVFInferiorRight coronary artery (RCA)
V1–V4Anterior/SeptalLeft anterior descending (LAD)
I, aVL, V5–V6LateralLeft circumflex (LCX)

EKG Paper and Grid

The EKG machine records electrical activity on a graph paper moving at a standard speed of 25 mm/sec.

The vertical axis measures voltage (1mV = 10 mm or 2 large squares) while the horizontal axis measures time

EKG grid

UnitVoltage/distance (vertical axis)Time (horizontal axis)
1 small square1mm0.04 seconds
1 large square5 mm0.20 seconds
5 large squares25 mm1.0 seconds

Calibration:

1 mV – 10 mm (2 large squares)

Electrical Direction and EKG Deflections

DirectionDeflection
Positive charge towards a positive electrodePositive deflection
Positive charge away from a positive electrodeNegative deflection
Electrical activity moving perpendicular to a leadIsoelectric (flat) line
Negative charge towards the negative electrodePositive deflection (seen in repolarisation)

Step-by-step Interpretation of an EKG

1. Confirm details and Calibration

Is the EKG recorded correctly and for the right patient?

  • Patient name, age, date, and time
  • Paper speed 25 mm/sec
  • Calibration 10 mm = 1 mv
  • Check for artifacts or poor lead placement

2. Rate

How fast is the heart beating?

The normal rate is 60 – 100 bpm.

  • Quick methods to calculate the rate
    • Large square method: 300 divided by the number of large squares between R waves.
    • Small square method: 1500 divided by the number of small squares between R waves
    • 6-second method for irregular rhythms: count QRS complexes in 6 seconds (30 large squares), then multiply by 10

3. Rhythm

Is the heartbeat regular, and is it sinus (P before every QRS)?

  • Characteristics of a normal sinus Rhythm
    • A P wave before every QRS
    • A QRS after every P wave
    • P waves all look the same
    • The R-R interval is constant
    • Rate of 60-100
    • The PR interval is not prolonged (0.12)
  • Quick method to check rhythm
    • Card method: lay a card along the EKG and mark the positions of three successive R waves. Slide the card to and fro, checking whether the intervals are equal.
  • Common rhythm patterns

4. Axis

Is the QRS axis normal, left, or right?

Axis is the overall direction of depolarization across the anterior chest. It is the sum of all ventricular electrical forces during depolarisation. Use lead I and aVF to quickly estimate the axis. Lead I looks at the heart from the left side (0 degrees) while aVF looks at the heart from the feet (90 degrees). The normal adult axis is approximately (-) 30 degrees to (+) 90 degrees.

Lead IaVFInterpretation
PositivePositiveNormal Axis
PositiveNegativeLeft Axis Deviation
NegativePositiveRight Axis Deviation
NegativeNegativeExtreme Axis

5. P wave morphology

How are the atria?

P-waves are evaluated mainly in lead II and V1. A P wave normally precedes each QRS complex. It is upright in II, III, and aVF but inverted in aVR.

  • Analyzing P waves
    • Are P waves present?
    • Is there exactly one P wave for every QRS complex?
    • Are the P waves upright in Lead II? (If the P wave is inverted, the signal may be starting from somewhere other than the SA node.)
  • P-wave abnormalities
    • Absent P wave: Atrial fibrillation
    • Hidden P wave: Junctional or ventricular rhythm
    • Bifid P wave: P mitrale indicating left atrial hypertrophy
    • Peaked P wave: P pulmonale indicating right atrial hypertrophy. Pseudo-p-pulmonale may be seen in hyperkalaemia

6. Intervals and Durations

Are the timings correct?

Is the PR interval normal in length?

Is the QRS narrow or wide?

Are there abnormal Q waves or unusual voltages?

Is the QT interval prolonged?

  • PR interval ranges from 0.12 – 0.20s (3 – 5 small squares)
  • QRS complex is normally < 0.12 seconds (3 small squares) wide
    • > 0.12 seconds (3 small squares): ventricular conduction defect (e.g. bundle branch block), metabolic disturbance, or ventricular origin (ventricular ectopic).
    • High amplitude QRS complex: ventricular hypertrophy
  • Q waves are < 0.04 s (1 small square) wide and < 2mm (2 small squares) deep. They are seen in leads I, aVL, V5, and V6 and reflect normal septal depolarization.
    • Deep and wide Q-waves: pathological Q waves occuring a few hours after an acute MI
  • QT interval varies with rate. QTc (corrected QT interval) is the QT interval divided by the square root of the R-R interval: QTc=QT/√RR. It is normally 0.38 – 0.42 seconds.

7. ST Segment and T waves

Is there ST elevation or depression?

Are the T waves upright and narrow?

  • ST segment should be flat (isoelectric)
    • ST elevation (> 1mm in limb leads and ≥ 2 mm in chest leads ): STEMI
    • ST depression (> 0.5 mm): NSTEMI or reciprocal changes
  • J point is where the S wave ends, and the ST segment starts
  • T waves should be upright in most leads. They are normally inverted in aVR, V1, and occasionally V2.
    • Tall and peaked T waves: hyperacute T waves seen in hyperkalaemia
    • Flattened T waves: seen in hypokalaemia
    • Inverted T waves: abnormal in leads I, II, and v4 – V6
    • U wave: a small wave after the T wave. Seen in hypokalaemia, bradycardia, and with certain drugs.
Reference Intervals
Biochemistry
ACTHP: <80 ng/L
ALTP: 5–35 U/L
AlbuminP: 35–50 g/L
AldosteroneP: 100–500 pmol/L
Alk. phosphataseP: 30–130 U/L
α-AmylaseP: 0–180 IU/dL
α-FetoproteinS: <10 kU/L
Angiotensin IIP: 5–35 pmol/L
ADHP: 0.9–4.6 pmol/L
ASTP: 5–35 U/L
BicarbonateP: 24–30 mmol/L
BilirubinP: 3–17 μmol/L
BNPP: <50 ng/L
CRPP: <10 mg/L
CalcitoninP: <0.1 mcg/L
Calcium (ionized)P: 1.0–1.25 mmol/L
Calcium (total)P: 2.12–2.60 mmol/L
ChlorideP: 95–105 mmol/L
CholesterolP: <5.0 mmol/L
VLDLP: 0.128–0.645 mmol/L
LDLP: <2.0 mmol/L
HDLP: 0.9–1.93 mmol/L
Cortisol AMP: 450–700 nmol/L
Cortisol MidnightP: 80–280 nmol/L
CK ♂P: 25–195 U/L
CK ♀P: 25–170 U/L
CreatinineP: 70–100 μmol/L
FerritinP: 12–200 mcg/L
FolateS: 2.1 mcg/L
FSHP: 2–8 U/L ♂; >25 menopause
GGT ♂P: 11–51 U/L
GGT ♀P: 7–33 U/L
Glucose (fasting)P: 3.5–5.5 mmol/L
Growth hormoneP: <20 mu/L
HbA1C (DCCT)B: 4–6%
HbA1C (IFCC)B: 20–42 mmol/mol
Iron ♂S: 14–31 μmol/L
Iron ♀S: 11–30 μmol/L
Lactate (venous)P: 0.6–2.4 mmol/L
Lactate (arterial)P: 0.6–1.8 mmol/L
LDHP: 70–250 U/L
LHP: 3–16 U/L
MagnesiumP: 0.75–1.05 mmol/L
OsmolalityP: 278–305 mosmol/kg
PTHP: 0.8–8.5 pmol/L
PotassiumP: 3.5–5.3 mmol/L
Prolactin ♂P: <450 U/L
Prolactin ♀P: <600 U/L
PSAP: 0–4 mcg/mL
Protein (total)P: 60–80 g/L
Red cell folateB: 0.36–1.44 μmol/L
Renin (erect)P: 2.8–4.5 pmol/mL/h
Renin (recumbent)P: 1.1–2.7 pmol/mL/h
SodiumP: 135–145 mmol/L
TBGP: 7–17 mg/L
TSHP: 0.5–4.2 mU/L
T4P: 70–140 nmol/L
Free T4P: 9–22 pmol/L
TIBCS: 54–75 μmol/L
TriglyceridesP: 0.50–2.3 mmol/L
T3P: 1.2–3.0 nmol/L
Troponin TP: <0.1 mcg/L
Urate ♂P: 210–480 μmol/L
Urate ♀P: 150–390 μmol/L
UreaP: 2.5–6.7 mmol/L
Vitamin B12S: 0.13–0.68 nmol/L
Vitamin DS: 50 nmol/L
Arterial Blood Gases
pH7.35–7.45
PaCO₂4.7–6.0 kPa
PaO₂>10.6 kPa
Base excess±2 mmol/L
Urine
Cortisol (free)<280 nmol/24h
Hydroxyindole acetic acid16–73 μmol/24h
Hydroxymethylmandelic acid16–48 μmol/24h
Metanephrines0.03–0.69 μmol/mmol cr.
Osmolality350–1000 mosmol/kg
17-Oxogenic steroids ♂28–30 μmol/24h
17-Oxogenic steroids ♀21–66 μmol/24h
17-Oxosteroids ♂17–76 μmol/24h
17-Oxosteroids ♀14–59 μmol/24h
Phosphate (inorganic)15–50 mmol/24h
Potassium14–120 mmol/24h
Protein<150 mg/24h
Protein/creatinine ratio<3 mg/mmol
Sodium100–250 mmol/24h
Haematology
WCC4.0–11.0 ×10⁹/L
RBC ♂4.5–6.5 ×10¹²/L
RBC ♀3.9–5.6 ×10¹²/L
Hb ♂130–180 g/L
Hb ♀115–160 g/L
PCV ♂0.4–0.54 L/L
PCV ♀0.37–0.47 L/L
MCV76–96 fL
MCH27–32 pg
MCHC300–360 g/L
RDW11.6–14.6%
Neutrophils2.0–7.5 ×10⁹/L (40–75%)
Lymphocytes1.0–4.5 ×10⁹/L (20–45%)
Eosinophils0.04–0.44 ×10⁹/L (1–6%)
Basophils0–0.10 ×10⁹/L (0–1%)
Monocytes0.2–0.8 ×10⁹/L (2–10%)
Platelets150–400 ×10⁹/L
Reticulocytes0.8–2.0% / 25–100 ×10⁹/L
Prothrombin time10–14 s
APTT35–45 s
Paediatric
Pulse Rate (bpm)
Neonate140–160
Infant <1yr120–140
1–5 years110–130
5–12 years80–120
>12 years70–100
Respiratory Rate (tachypnoea)
0–2 months≥60/min
2–12 months≥50/min
1–5 years≥40/min
>5 years≥30/min
Blood Pressure (mmHg)
Term65/45
1 year75/50
4 years85/60
8 years95/65
10 years100/70
Weight Formulas
3–12 months(a + 9)/2 kg
1–6 years2a + 8 kg
>6 years(7a − 5)/2 kg
Haemoglobin (g/dL)
Term newborn13–20
1 month11–18
2 months10–15
1–2 years10–13
>2 years11–14
MUAC (6 months–5 years)
Obese>17.5 cm
Normal13.5–17.4 cm
At risk12.5–13.4 cm
Moderate malnutrition11.5–12.4 cm
Severe malnutrition<11.5 cm
Developmental Milestones
Social smile1.5 months
Head control4 months
Sits unsupported7 months
Crawls10 months
Stands unsupported10–12 months
Walks12–13 months
Talks18 months
CSF WBC (/mm³)
Term newborn0–25
>2 weeks0–5
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