TOTW #5 - Immunology Start QuizPage 1 of 25 Which one of the following is false regarding humoral immunity? Provides defence against extracellular microbes Mediated by B-lymphocytes Recognises unprocessed antigens Acts on tumor cells Page 2 of 25 Which of the following refers to a type of immunity produced actively by the hosts immune system after a clinical or inapparent infection? Passive natural immunity Passive artificial immunity Active natural immunity Active artificial immunity Page 3 of 25 Select the incorrectly matched toll-like receptor TLR-3 - double-stranded RNA TLR-5 - gram positive bacteria TLR-7 - single-stranded RNA TLR-4 - bacterial LPS (endotoxin) Page 4 of 25 Which of the following microbes evades the immune system by resisting complement activation? Neisseria meningitidis Pseudomonas Staphylococci Pneumococci Page 5 of 25 Which of the following immunoglobulin isotypes is secreted as a pentamer? IgA IgD IgM IgE Page 6 of 25 Which immunoglobulin is primarily involved in allergic reactions and defense against parasitic infections? IgA IgE IgG IgM Page 7 of 25 What is the primary function of Helper T cells in the immune response? Phagocytosis of pathogens Direct killing of infected cells Activation of other immune cells Production of antibodies Page 8 of 25 Which of the following is a characteristic feature of the adaptive immune response? Rapid response upon re-exposure to the same pathogen Immediate response to any pathogen Non-specific recognition of pathogens Present from birth without prior exposure Page 9 of 25 Which type of immune response is associated with granuloma formation? Humoral immune response Cell-mediated immune response Innate immune response Passive immune response Page 10 of 25 What is the primary role of plasma cells in the immune system? Phagocytosis of pathogens Antigen presentation Production of antibodies Activation of T cells Page 11 of 25 Which is the most common inherited immunodeficiency? Bruton’s X-linked agammaglobulinemia Common variable immunodeficiency Severe combined immunodeficiency Selective IgA deficiency Page 12 of 25 In the lymph node, dendritic cells would be found in the Outer cortex Primary follicle Germinal center Medulla Page 13 of 25 Certain drugs may trigger an autoimmune response. Drug-induced Lupus antibodies are? Anti-Ro antibodies Anti-histone antibodies Anti-U1 ribonucleoprotein antibodies Anti-dsDNA antibodies Page 14 of 25 Which of the following interleukins is being used as immunotherapy for renal cell carcinoma and metastatic melanoma? Interleukin-1 Interleukin-2 Interleukin-5 Interleukin-10 Page 15 of 25 A 1-year-old boy has repeated upper respiratory infections. Stool examination shows giardia lamblia cysts. Which of the following laboratory findings will likely be useful in this boy? Deficiencies of C5-C9 Low or absent immunoglobulins Selective IgA deficiency Antibodies to Human Immunodeficiency Virus Page 16 of 25 Which of the following is a cell mediated hypersensitivity reaction? Type 1 Type 2 Type 3 Type 4 Page 17 of 25 SCID(Severe Combined Immunodeficiency) can occur due to the absence of which of the following enzymes? Adenosine deaminase Guanosine deaminase Phosphorylase Thymidine deaminase Page 18 of 25 Fusion between a plasma cell and a tumour cell creates a: Natural killer cell Hybridoma Myeloma Lymphoblast Page 19 of 25 The complement component that is strongly chemotactic for neutrophils is: C3a C3b C5a C5b Page 20 of 25 Which of the following antibody is an important host defense against encapsulated bacteria? IgG1 IgG2 IgG3 IgG4 Page 21 of 25 Of the following diseases, which one is the most likely to be caused by a delayed hypersensitivity reaction? Autoimmune hemolytic anaemia Contact dermatitis Hemolytic disease of the newborn Poststreptococcal Glomerulonephritis Page 22 of 25 Inability to distinguish self cells from non self cells may lead to Hypersensitivity Autoimmune diseases Immunodeficiency Tolerance Page 23 of 25 In severe combined immune deficiency (SCID) the patients are deficient of B cells T cells Both B and T cells IgA Page 24 of 25 A 14-year-old male child with extensive third-degree burns from a house fire receives a skin graft. Skin grafted from which donor has the lowest risk of immunologic rejection? The patient The patient’s father The patient’s fraternal twin brother The patient’s fraternal twin sister Page 25 of 25 A 10-year-old male child has seasonal episodes of runny nose, sneezing, nasal congestion, and itchy, watery eyes. His symptoms are most severe in the spring and interfere with school performance and outside activities. His symptoms have not been well controlled with over-the-counter antihistamines and his physician prescribes a medication that inhibits the cysteinyl leukotriene receptor. Which of the following drugs was he given? Beclomethasone Diphenhydramine Loratadine Montelukast Multiple Authors | WebsiteTOTW #26 - MicrobiologyTOTW #25 - PsychiatryTOTW #24 - BiochemistryTOTW #23 - Haematology Previous Post Mastering Learning: The Feynman Technique's Genius Approach to Active Learning Next Post Time Management: Tips for Balancing Work, Study, and Social Life