Management of Chronic Wounds

Overview

The goal of managing chronic wound is to identify and address the conditions that impair wound healing. By correcting these condition, the wound behaves like an acute wound and can be managed as such through closure, skin graft, or flap.

In addition to correcting these condition, supportive management (proper wound care and dressing) aims to create a wound bed that is sufficient for epithelialization or support a skin graft. This can be done by:

  1. Reducing infection or colonization
  2. Maintaining appropriate moisture levels
  3. Improving oxygen tension in the tissue
  4. Promoting angiogenesis

Dressing

Category of DressingCharacteristicUseExample
Non-adherent dressingFine mesh gauze with coating (to prevent adherence)To protect wounds and underlying tissue, maintain moistureVaseline gauze, Xeroform, Mepitel, Telfa, Tulle gras
Absorptive dressing
GauzeWide mesh gauzeTo remove exudate, prevent maceration, and debride (wet-to-dry application)Wide mesh gauze
FoamsHydrophobic foam sheetTo protect wounds and absorb exudateAllevyn, Curfoam
Occlusive dressing
Non-biologicMade of polyurethane, cellulose, among othersTo insulate, retain moisture, protect the wound and decrease bacterial contaminationTegaderm, Opsite, Duoderm, Melgisorb
BiologicMade from cadaver skin, pig skin, and human amniotic sacTo insulate, retain moisture, protect the wound and decrease bacterial contaminationCadaveric skin, Bovine xenograft, Integra, Alloderm
Creams, Ointments, and Solutions
Antibacterial solutionA variety existUse on infected woundsAcetic acid (gram negatives, Pseudomonas), Dakin’s solution (broad spectrum), Iodine-containing solution (broad spectrum, antifungal), Silve-containig solution (broad spectrum, antifungal)
Antibacterial ointmentsA variety existUse on infected wounds, provides occlusion and soothes the woundBacitracin (gram positive), Neomycin (gram negative), polymyxin B (gram negative), Neomycin, Triple antibiotic ointment (bacitracin, neomycin, polymyxin B)
EnzymaticA variety existTo remove necrotic tissueCollagenase, papain

Hyperbaric Oxygen (HBO)

HBO therapy involves inhaling 100% O2 at 1.9-2.5 atm of pressure allowing tissue oxygen tension to be ten times normal. It can be given in an enclosed chamber or through a face mask. The oxygen is used in metabolism, induces the synthesis of nitric oxide synthase, and promotes angiogenesis.

HBO is useful in diabetic ischemic ulcers (reduces the amputation rates)

Negative Pressure Wound Therapy (Wound VAC)

Wound VAC applies negative pressure to the wound to remove chronic edema, increase local blood flow and stimulate the proliferation of granulation tissue. It may be used on acute or chronic wounds.

Unna Boot

An unna boot is made by wrapping the leg in gauze impregnated with zinc, glycerin, calamine, or a mixture. It is used to treat venous leg ulcers and lymphedema-related ulcers. The hardened gauze restricts the outward movement of the calf mucles and promotes edema resorption and venous return.

Dr. Jeffrey Kalei
Dr. Jeffrey Kalei

Author and illustrator for Hyperexcision. Interested in emergency room medicine. I have a passion for medical education and drawing.

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