Major Histocompatibility Complex Molecules

Updated on November 12, 2024 Differentiate between MHC class I and MHC Class II molecules MHC IMHC IIPolypeptide chaina-chain, B2-microglobulina-chain and B-chainT-cell receptor binding siteA3 binds to CD8B2 region binds to CD4Size of peptide binding cleft8-10 amino acid residues13-18 amino acid residuesNomenclatureHLA-A, HLA-B, HLA-CHLA-DR, HLA-DQ, HLA-DPPolymorphic residuea1 and a2 domains-ExpressionAlmost all nucleated cellsProfessional antigen presenting...

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Jeffrey Kalei
Jeffrey Kalei
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