Haemorrhoids

Last updated: November 17, 2025
Table Of Contents

Hemorrhoids

Haemorrhoids are dilated submucosal veins within the internal or external anal canal that are usually inflamed or thrombosed. They usually occur at the 3 o’clock, 7 o’clock and 11 o’clock positions. A digital rectal examination is diagnostic for haemorrhoids. Haemorrhoids can be classified as internal, external and combined. Combined haemorrhoids most often require hemorrhoidectomy. Grading of haemorrhoids is based on reducibility (not on appearance).

Internal vs external haemorrhoids

Internal hemorrhoidExternal hemorrhoid
LocationProximal to dentate lineDistal to dentate line
CausesIncreased intra-abdominal pressure (local, pelvic, abdominal and neurological causes)Extension of internal hemorrhoids (interno-external hemorrhoids), straining, cooughing, lifting heavy weight
InnervationAutonomicSomatic
PainNot painfulOften painful
Bleedoften bleedsusually does not bleed

Causes of hemorrhoids

ClassificationCauses
LocalAnorectal deformity, hypotonic anal sphincter, anorectal carcinoma
PelvicGravid uterus, fibroids, carcinoma of the uterus or cervix, ovarian neoplasm, bladder carcinoma
AbdominalAscites
NeurologicalParaplegia, multiple sclerosis

Classification (Grading) of internal hemorrhoids

GradeFinding on DRETreatent
Grade INo prolapse outside anal canal. Only associated with bleeding.Conservative medical treatment and lifestyle modifications
Grade IIProlapse outside anal canal with valsava, spontaneously reduces at restRubber band ligation, Sclerotherapy
Grade IIIProlapse outside anal canal with valsava, manually reducableRubber band ligation, Sclerotherapy, coagulation, hemorrhoidectomy if symptomatic
Grade IVProlapse outside anal canal without valsava, cannot be manually reduced. May be strangulated, thrombosed, or ulcerated.Hemorrhoidectomy
  • Risk factors for hemorrhoids
    • Excessive straining (chronic constipation, chronic cough, heavy lifting, BPH)
    • Extended sitting (sedentary lifestyle)
    • Pregnancy (third trimester)
    • Older age (due to laxity of veins)
    • Connective tissue disorders (Ehlers-Danlos, Scleroderma)
    • Portal hypertension
    • Colon cancer
    • Inflammatory bowel disease
    • Spinal cord injury
    • Rectal surgery
    • Episiotomy
    • Anal intercourse
  • Patient history (increased abdominal pressure)
    • Constipation
    • Athletes
    • Inflammatory bowel disease
    • Pregnant
    • Manual work
    • Liver disease
    • Anybody can get haemorrhoids
  • Signs and symptoms
    • Painless bright red blood per rectum (small in amount, seen on the toilet paper after bowel movement)
    • Perianal mass (in case of prolapse)
    • Perianal pruritus (due to bleeding and prolapse)
    • Severe perianal pain (in case of external hemorrhoid and prolapse)
    • Anal discharge (mucoid and contains fecal debris)
  • Investigations
    • Anoscopy
  • Differentials
    • Anal fissure: younger women with tight rectum. Painful BRBPR.
    • Anal skin tags
    • Proctitis
    • Rectal prolapse
  • Conservative treatment
    • Increase fibre in the diet
    • Increase fluid intake
    • Avoid fatty foods
    • Exercise regularly
    • Treat constipation with stool softeners (docusate) or laxatives (polyethylene glycol)
  • Indications for hemorrhoidectomy
    • Third and fourth degree hemorhroids
    • Secondary degree hemorrhoids not cure by non-operative treatment
    • Fibrosed hemorrhoids
    • Interno-external hemorrhoids with well defined external hemorrhoids

Treatment options for hemorrhoids

TreatmentDescription
Symptomatic treatmentAdvise on defectaory habits, diet, stool softeners and bulking agents
Injection sclerotherapySubmucosal injection of 5% phenol in arachis oil or almond oil. Complications may include sepsis, prostatitis, impotence and rectovaginal fistula.
Rubber band ligationUsing a Barron’s bander, elastic bands are applied on the base of the pedicle of each hemorrhoid proximal to the dentate line leading ot ischaemic necrosis and sloughing within 10 days
Open hemorrhoidectomy (Milligan-Moragn operation)Ligation and excision of the hemorrhoid. The anal mucosa and skin are left open to heal by seondary intention
Closed hemorrhoidectomy (Ferguson operation)Ligation and excision of the hemorrhoid. The mucosal defect is closed with continuous sutture after undermining the anoderm on each side
Stapled hemorrhoidopexyRemoval of a strip of rectal mucosa and submucosa proximal to the dentate line then closing the defect using a stapling gun. This causes the hemorrhoids to move up (fixation) and reduces blood flow to hemorrhoids. Has a higher recurrence rate than conventional hemorrhoidectomy.
Transanal-Hemorrhoidal deearterialisation (THD) or Haemorrhoid artery ligation operation (HALO)Use transanal doppler to guide ligaiton of vessels feeding the hemorhroid. Recurrence rates for fourth degree hemorrhoids is high but has better complication rate and post-operative pain

Treatment of complications of hemorrhoids

ComplicationsTreatment
Thrombosis, ulceration and strangulationConservative approach for pain and pruritus with sitz baths, topical anaesthetic (lidocaine), corticosteroids (hydrocortisone) or vasoconstrictors (phenylephrine). Subtototal hemorrhoidectomy can be performed emergently
BleedingLocal compress containing adrenaline, resuscitation, rubber band ligation and hemorrhoidectomy
  • Contraindications to hemorrhoidectomy and band-ligation
    • Rectal varices: present in patients with portal hypertension. There is a risk of massive bleeding post-operatively
    • Coagulopathy (cirrhosis or on anticoagulants)
  • Complications of hemorrhoids
    • Strangulation and thormbosis
    • Ulceration
    • Gangrene
    • Portal pyaemia
    • Fibrosis

Complications of hemorrhoidectomy

ClassificationComplications
EarlyPain (requires opiate analgesia), acute urinary retention (especially in men), reactionary hemorrhage (more common than secondary hemorrhage)
LateSecondary hemorrhage (uncommon), anal stricture, anal fissure, submcous abscesses, incontinence (due to damage of the underlying internal sphincter)
Reference Intervals
Biochemistry
ACTHP: <80 ng/L
ALTP: 5–35 U/L
AlbuminP: 35–50 g/L
AldosteroneP: 100–500 pmol/L
Alk. phosphataseP: 30–130 U/L
α-AmylaseP: 0–180 IU/dL
α-FetoproteinS: <10 kU/L
Angiotensin IIP: 5–35 pmol/L
ADHP: 0.9–4.6 pmol/L
ASTP: 5–35 U/L
BicarbonateP: 24–30 mmol/L
BilirubinP: 3–17 μmol/L
BNPP: <50 ng/L
CRPP: <10 mg/L
CalcitoninP: <0.1 mcg/L
Calcium (ionized)P: 1.0–1.25 mmol/L
Calcium (total)P: 2.12–2.60 mmol/L
ChlorideP: 95–105 mmol/L
CholesterolP: <5.0 mmol/L
VLDLP: 0.128–0.645 mmol/L
LDLP: <2.0 mmol/L
HDLP: 0.9–1.93 mmol/L
Cortisol AMP: 450–700 nmol/L
Cortisol MidnightP: 80–280 nmol/L
CK ♂P: 25–195 U/L
CK ♀P: 25–170 U/L
CreatinineP: 70–100 μmol/L
FerritinP: 12–200 mcg/L
FolateS: 2.1 mcg/L
FSHP: 2–8 U/L ♂; >25 menopause
GGT ♂P: 11–51 U/L
GGT ♀P: 7–33 U/L
Glucose (fasting)P: 3.5–5.5 mmol/L
Growth hormoneP: <20 mu/L
HbA1C (DCCT)B: 4–6%
HbA1C (IFCC)B: 20–42 mmol/mol
Iron ♂S: 14–31 μmol/L
Iron ♀S: 11–30 μmol/L
Lactate (venous)P: 0.6–2.4 mmol/L
Lactate (arterial)P: 0.6–1.8 mmol/L
LDHP: 70–250 U/L
LHP: 3–16 U/L
MagnesiumP: 0.75–1.05 mmol/L
OsmolalityP: 278–305 mosmol/kg
PTHP: 0.8–8.5 pmol/L
PotassiumP: 3.5–5.3 mmol/L
Prolactin ♂P: <450 U/L
Prolactin ♀P: <600 U/L
PSAP: 0–4 mcg/mL
Protein (total)P: 60–80 g/L
Red cell folateB: 0.36–1.44 μmol/L
Renin (erect)P: 2.8–4.5 pmol/mL/h
Renin (recumbent)P: 1.1–2.7 pmol/mL/h
SodiumP: 135–145 mmol/L
TBGP: 7–17 mg/L
TSHP: 0.5–4.2 mU/L
T4P: 70–140 nmol/L
Free T4P: 9–22 pmol/L
TIBCS: 54–75 μmol/L
TriglyceridesP: 0.50–2.3 mmol/L
T3P: 1.2–3.0 nmol/L
Troponin TP: <0.1 mcg/L
Urate ♂P: 210–480 μmol/L
Urate ♀P: 150–390 μmol/L
UreaP: 2.5–6.7 mmol/L
Vitamin B12S: 0.13–0.68 nmol/L
Vitamin DS: 50 nmol/L
Arterial Blood Gases
pH7.35–7.45
PaCO₂4.7–6.0 kPa
PaO₂>10.6 kPa
Base excess±2 mmol/L
Urine
Cortisol (free)<280 nmol/24h
Hydroxyindole acetic acid16–73 μmol/24h
Hydroxymethylmandelic acid16–48 μmol/24h
Metanephrines0.03–0.69 μmol/mmol cr.
Osmolality350–1000 mosmol/kg
17-Oxogenic steroids ♂28–30 μmol/24h
17-Oxogenic steroids ♀21–66 μmol/24h
17-Oxosteroids ♂17–76 μmol/24h
17-Oxosteroids ♀14–59 μmol/24h
Phosphate (inorganic)15–50 mmol/24h
Potassium14–120 mmol/24h
Protein<150 mg/24h
Protein/creatinine ratio<3 mg/mmol
Sodium100–250 mmol/24h
Haematology
WCC4.0–11.0 ×10⁹/L
RBC ♂4.5–6.5 ×10¹²/L
RBC ♀3.9–5.6 ×10¹²/L
Hb ♂130–180 g/L
Hb ♀115–160 g/L
PCV ♂0.4–0.54 L/L
PCV ♀0.37–0.47 L/L
MCV76–96 fL
MCH27–32 pg
MCHC300–360 g/L
RDW11.6–14.6%
Neutrophils2.0–7.5 ×10⁹/L (40–75%)
Lymphocytes1.0–4.5 ×10⁹/L (20–45%)
Eosinophils0.04–0.44 ×10⁹/L (1–6%)
Basophils0–0.10 ×10⁹/L (0–1%)
Monocytes0.2–0.8 ×10⁹/L (2–10%)
Platelets150–400 ×10⁹/L
Reticulocytes0.8–2.0% / 25–100 ×10⁹/L
Prothrombin time10–14 s
APTT35–45 s
Paediatric
Pulse Rate (bpm)
Neonate140–160
Infant <1yr120–140
1–5 years110–130
5–12 years80–120
>12 years70–100
Respiratory Rate (tachypnoea)
0–2 months≥60/min
2–12 months≥50/min
1–5 years≥40/min
>5 years≥30/min
Blood Pressure (mmHg)
Term65/45
1 year75/50
4 years85/60
8 years95/65
10 years100/70
Weight Formulas
3–12 months(a + 9)/2 kg
1–6 years2a + 8 kg
>6 years(7a − 5)/2 kg
Haemoglobin (g/dL)
Term newborn13–20
1 month11–18
2 months10–15
1–2 years10–13
>2 years11–14
MUAC (6 months–5 years)
Obese>17.5 cm
Normal13.5–17.4 cm
At risk12.5–13.4 cm
Moderate malnutrition11.5–12.4 cm
Severe malnutrition<11.5 cm
Developmental Milestones
Social smile1.5 months
Head control4 months
Sits unsupported7 months
Crawls10 months
Stands unsupported10–12 months
Walks12–13 months
Talks18 months
CSF WBC (/mm³)
Term newborn0–25
>2 weeks0–5
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