Gastrointestinal Bleeding

Table Of Contents

Gastrointestinal Bleeding

Primary SymptomsDifferentials
Hematemesis or MelenaRuptured Oesophageal varices, Dieulafoys’s lesion, PUD, Meckel’s diverticulum, Gastric or esophageal cancer, Mallory-Weiss tear, Celiac disease, Esophagitis, Gastritis, Aortoenteric fistula
HematocheziaDiverticulosis, Angiodysplasia, Intussusception, Colon cancer, Hemorrhoids, IBD, Ischemic colitis, Infectious diarrhoea

A patients who present with at least one Gastrointestinal “ALARM” symptom needs an EGD

  • Gastrointestinal “ALARM Symptoms”
    • Anemia, Age > 45y
    • Loss of weight (unintended)
    • Anorexia or Early satiety
    • Recently progressive symptoms
    • Melena/ Hematemesis/Hematochezia/ Heme + stool
    • Symptoms present for > 6 month, Odynophagia, Dysphagia
  • Initial management of upper gastrointestinal bleeding
    • Resuscitation
      • Secure airway
      • Two peripheral Large bore IV access points
      • Bolus Fluids if significant recent loss (vomiting or hematemesis)
    • Nasogastric tube with lavage: diagnostic and prognostic for UGIB
    • Upper GI Endoscopy (EGD)
    • Pharmacotherapy
      • Intravenous PPIs e.g. esomeprazole**:** Protect stomach and duodenum
      • Intravenous octreotide: if the cause is variceal bleed
      • Intravenous ceftriaxone or fluoroquinolole: for prophylaxis against SBP in patients with ascites
    • Laboratory investigations
      • CBC
      • LFTs: to rule out hepatic causes
      • GXM with blood products on hand
      • PT/PTT
  • Initial management of lower gastrointestinal bleeding (LGIB)
    • Resuscitation
      • Secure airway
      • Two peripheral large-bore IV access points
      • Bolus fluids if significant recent loss (vomiting, hematochezia, diarrhea)
    • NG tube with lavage (to rule out UGIB; UGI endoscopy eventually to definitively rule out UGIB)
    • Colonoscopy
    • Laboratory tests
      • CBC
      • PT/PTT
      • GXM blood products on hand
Dr. Jeffrey Kalei
Dr. Jeffrey Kalei

Author and illustrator for Hyperexcision. Interested in emergency room medicine. I have a passion for medical education and drawing.

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