Femoral Shaft Fracture

Last updated: November 17, 2025
Table Of Contents

Femoral Shaft Fracture

Femoral shaft fractures are fractures of the diaphysis of the femur. They have a bimodal distribution with high-energy mechanisms in young individuals and low-energy mechanisms in older osteoporotic patients. Closed fractures can lose 1000 – 1500 ml of blood, while open fractures lose 2000 – 3000 ml of blood. They carry a high risk of fat embolism (especially bilateral femur fractures) and are often associated with other life-threatening injuries. Open femoral shaft fractures are an orthopaedic EMERGENCY and require surgical treatment within 6 hours. Most femoral shaft fractures are managed operatively unless the patient is too sick to be operated on or refuses surgery.

Winquist and Hansen Classification: historical classification used to determine whether the femoral shaft fracture required locking, weight-bearing status post-op and prognosis, e.g. degree of malunion. It is not useful nowadays due to the full locking capabilities of implants and full post-op weight bearing with IM nails.

ClassificationDescription
Type 0No comminution
Type IInsignificant amount of comminution
Type IIComminution with greater than 50% cortical contact
Type IIIComminution with less than 50% of cortical contact
Type IVSegmental fracture with no cortical contact between the proximal and distal fragment
  • Anatomy
    • The femoral shaft has an anterior bow with an isthmus (narrowest part of the intramedullary canal)
    • It has a linea aspera in the posterior cortex that acts as a compressive strut against the anterior bow
    • The medial cortex is under compression while the lateral cortex is under tension
    • The thigh has 3 compartments – anterior posterior and adductor compartment
      • Anterior compartment includes sartorius and quadriceps
      • Posterior compartment concists biceps femoris, semitendinosus and semimembranosus
      • Adductor compartments consists of gracilis, adductor longus, adductor brevis and adductor magnus
    • The 2 major arteries include the:
      • Profunda femoris: disruption leads to hemorrhage
      • Superficial femoral: disruption leads to distal ischemia since it enters the distal extremity as the popliteal artery
    • Significant nerves include the sciatic, femoral and obturator nerve. Sciatic nerve damage is most concerning
  • Deforming forces
    • Proximal flexion by the iliopsoa
    • Proximal abduction by the gluteus minimus and medius
    • Distal adduction by adductors
    • Distal flexion by the gastrocnemius
  • Mechanisms
    • High-energy mechanism
      • High-speed MVA (most common mechanism)
    • Low-energy mechanism
      • Fall from standing height
      • Gunshot
  • Associated injuries
    • Ipsilateral femoral neck fracture (2 – 6%, vertically oriented non-displaced basicervical, easy to miss)
    • Bilateral femoral shaft fracture (significant risk of pulmonary embolism and increased mortality)
    • Ipsilateral tibia shaft fracture
    • Ipsilateral acetabular fracture
  • Signs and symptoms
    • Severe thigh pain
    • Tenseness
    • Tenderness and swelling
    • Limb length shortening
    • External rotation (not all the time)
  • Physical examination
    • Swollen thigh
    • Thigh tenderness
    • Shortening of the affected limb
    • Neurovascular examination
  • Investigations
    • X-ray: AP and lateral view of the hip-joint, full-length femur and knee joint
      • AP internal rotation 15 – 20 degreees hip X-ray
    • CT-scan fo the hip: to rule out associated femoral neck fracture
      • 1 mm capsular distension between injured and uninjured sides on the axial soft tissue window (capsular sign)
    • CBC, ESR, CRP
  • Imaging to rule out ipsilateral femoral neck fracture
    • 10 degrees internal rotation AP hip radiograph (femoral neck is placed in profile)
    • Fine-cut CT-scan of the hip
    • Intra-operative AP and lateral fluoroscopy of the ipsilateral hip
    • Post-operative hip x-rays
  • Initial management of femoral shaft fracture
    • Thomas splint
    • Skeletal traction
      • 15% of patient body weight to pins
      • Distal femur pin (medial to lateral to avoid injuring the femoral artery), or
      • Proximal tibia pin ( 2 cm posterior and 2cm inferior of the tibial tuberosity lateral to medial to avoid injury to the common peroneal nerve)
    • Cutaneous traction (Bucks traction)
  • Non-operative treatment of femoral shaft fractures
    • Long-leg cast or hip spica for paediatric patients or non-operative candidates
  • Operative treatment
    • External fixator: temporary stabilization for damage control orthopaedics. Converted to nail in 2 – 3 weeks
    • Open reduction internal fixation (ORIF) with plate: has an increased risk of infection, non-union and failure
    • Locked Intramedullary (IM) nail: preferred mode of treatment. Rate of malunion increased when the starting point is opposite the fracture site e.g. antegrade nail for a distal femoral shaft fracture. Reaming increases union, decreases time to union with no change in pulmonary complications
      • Antegrade, reamed, locked IM nail is gold standard
      • Dynamic lock for transverse fracture
      • Static lock for all other fracture patterns
      • Antegrade nail can be placed via piriformis or trochanteric entry point
      • Retrograde nail is placed intercondylar anterior to Blumensaat’s line or medial condylar
  • Complications of antegrade nails
    • Hip pain
    • Abductor or quadricep weakness
    • Reduced hip range of motion
    • Heterotopc ossification
    • Iatrogenic femoral neck fracture
  • Complications of retrograde nails
    • Knee pain
    • Cartilage injury
    • Cruciate ligament injury if starting posterior to Blumensaat’s line
  • Complications of femoral shaft fracture
    • Shock
    • Fat embolism
    • Deep venous thrombosis
    • Pulmonary embolism
    • Heterotopic ossification
    • Avascular necrosis
    • Pudendal nerve injury (10%, excessive traction on fracture table, presents with erectile dysfunction)
    • Peroneal nerve injury
    • Compartment syndrome (non-injured legs in hemilithotomy position, more common in ballistic injuries compared to blunt injury)
    • Femoral artery or nerve injry
    • Anterior perforation of distal femur if there is a nail/femur radius of curvature mismatch
    • Iatrogenic femoral neck fracture
    • Delayed-union
    • Aseptic non-union
    • Septic non-union
    • Malunion
    • Implant failure
    • Hip pain or limp from antegrade nail
    • Knee pain or retro-patellar arthritis from a retrograde nail
Reference Intervals
Biochemistry
ACTHP: <80 ng/L
ALTP: 5–35 U/L
AlbuminP: 35–50 g/L
AldosteroneP: 100–500 pmol/L
Alk. phosphataseP: 30–130 U/L
α-AmylaseP: 0–180 IU/dL
α-FetoproteinS: <10 kU/L
Angiotensin IIP: 5–35 pmol/L
ADHP: 0.9–4.6 pmol/L
ASTP: 5–35 U/L
BicarbonateP: 24–30 mmol/L
BilirubinP: 3–17 μmol/L
BNPP: <50 ng/L
CRPP: <10 mg/L
CalcitoninP: <0.1 mcg/L
Calcium (ionized)P: 1.0–1.25 mmol/L
Calcium (total)P: 2.12–2.60 mmol/L
ChlorideP: 95–105 mmol/L
CholesterolP: <5.0 mmol/L
VLDLP: 0.128–0.645 mmol/L
LDLP: <2.0 mmol/L
HDLP: 0.9–1.93 mmol/L
Cortisol AMP: 450–700 nmol/L
Cortisol MidnightP: 80–280 nmol/L
CK ♂P: 25–195 U/L
CK ♀P: 25–170 U/L
CreatinineP: 70–100 μmol/L
FerritinP: 12–200 mcg/L
FolateS: 2.1 mcg/L
FSHP: 2–8 U/L ♂; >25 menopause
GGT ♂P: 11–51 U/L
GGT ♀P: 7–33 U/L
Glucose (fasting)P: 3.5–5.5 mmol/L
Growth hormoneP: <20 mu/L
HbA1C (DCCT)B: 4–6%
HbA1C (IFCC)B: 20–42 mmol/mol
Iron ♂S: 14–31 μmol/L
Iron ♀S: 11–30 μmol/L
Lactate (venous)P: 0.6–2.4 mmol/L
Lactate (arterial)P: 0.6–1.8 mmol/L
LDHP: 70–250 U/L
LHP: 3–16 U/L
MagnesiumP: 0.75–1.05 mmol/L
OsmolalityP: 278–305 mosmol/kg
PTHP: 0.8–8.5 pmol/L
PotassiumP: 3.5–5.3 mmol/L
Prolactin ♂P: <450 U/L
Prolactin ♀P: <600 U/L
PSAP: 0–4 mcg/mL
Protein (total)P: 60–80 g/L
Red cell folateB: 0.36–1.44 μmol/L
Renin (erect)P: 2.8–4.5 pmol/mL/h
Renin (recumbent)P: 1.1–2.7 pmol/mL/h
SodiumP: 135–145 mmol/L
TBGP: 7–17 mg/L
TSHP: 0.5–4.2 mU/L
T4P: 70–140 nmol/L
Free T4P: 9–22 pmol/L
TIBCS: 54–75 μmol/L
TriglyceridesP: 0.50–2.3 mmol/L
T3P: 1.2–3.0 nmol/L
Troponin TP: <0.1 mcg/L
Urate ♂P: 210–480 μmol/L
Urate ♀P: 150–390 μmol/L
UreaP: 2.5–6.7 mmol/L
Vitamin B12S: 0.13–0.68 nmol/L
Vitamin DS: 50 nmol/L
Arterial Blood Gases
pH7.35–7.45
PaCO₂4.7–6.0 kPa
PaO₂>10.6 kPa
Base excess±2 mmol/L
Urine
Cortisol (free)<280 nmol/24h
Hydroxyindole acetic acid16–73 μmol/24h
Hydroxymethylmandelic acid16–48 μmol/24h
Metanephrines0.03–0.69 μmol/mmol cr.
Osmolality350–1000 mosmol/kg
17-Oxogenic steroids ♂28–30 μmol/24h
17-Oxogenic steroids ♀21–66 μmol/24h
17-Oxosteroids ♂17–76 μmol/24h
17-Oxosteroids ♀14–59 μmol/24h
Phosphate (inorganic)15–50 mmol/24h
Potassium14–120 mmol/24h
Protein<150 mg/24h
Protein/creatinine ratio<3 mg/mmol
Sodium100–250 mmol/24h
Haematology
WCC4.0–11.0 ×10⁹/L
RBC ♂4.5–6.5 ×10¹²/L
RBC ♀3.9–5.6 ×10¹²/L
Hb ♂130–180 g/L
Hb ♀115–160 g/L
PCV ♂0.4–0.54 L/L
PCV ♀0.37–0.47 L/L
MCV76–96 fL
MCH27–32 pg
MCHC300–360 g/L
RDW11.6–14.6%
Neutrophils2.0–7.5 ×10⁹/L (40–75%)
Lymphocytes1.0–4.5 ×10⁹/L (20–45%)
Eosinophils0.04–0.44 ×10⁹/L (1–6%)
Basophils0–0.10 ×10⁹/L (0–1%)
Monocytes0.2–0.8 ×10⁹/L (2–10%)
Platelets150–400 ×10⁹/L
Reticulocytes0.8–2.0% / 25–100 ×10⁹/L
Prothrombin time10–14 s
APTT35–45 s
Paediatric
Pulse Rate (bpm)
Neonate140–160
Infant <1yr120–140
1–5 years110–130
5–12 years80–120
>12 years70–100
Respiratory Rate (tachypnoea)
0–2 months≥60/min
2–12 months≥50/min
1–5 years≥40/min
>5 years≥30/min
Blood Pressure (mmHg)
Term65/45
1 year75/50
4 years85/60
8 years95/65
10 years100/70
Weight Formulas
3–12 months(a + 9)/2 kg
1–6 years2a + 8 kg
>6 years(7a − 5)/2 kg
Haemoglobin (g/dL)
Term newborn13–20
1 month11–18
2 months10–15
1–2 years10–13
>2 years11–14
MUAC (6 months–5 years)
Obese>17.5 cm
Normal13.5–17.4 cm
At risk12.5–13.4 cm
Moderate malnutrition11.5–12.4 cm
Severe malnutrition<11.5 cm
Developmental Milestones
Social smile1.5 months
Head control4 months
Sits unsupported7 months
Crawls10 months
Stands unsupported10–12 months
Walks12–13 months
Talks18 months
CSF WBC (/mm³)
Term newborn0–25
>2 weeks0–5
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