Distal Femur Fracture

Last updated: November 17, 2025
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Distal femur fractures invole the distal metaphyseal-diaphyseal junction of the femur +/- intra-articular extention to the femoral condyles. Majority of distal femur fractures are treated operatively.

Fractures of the distal femur account for 7% of femur fractures. Like most fractures it has a bimodal distribution with high-energy mechanism is common in the young population while low-energy mechanism is more common in the elderly.

AO/OTA Classification of distal femur fracture

CategoryAO/OTAAO/OTA
BoneFemur3
LocationDistal segment33
TypesExtra-articular (A)33-A
Partial-articular (B)33-B (33 – B3 is a Hoffa fragment)
Complete articular (C)33 – C
  • Anatomy
    • Shaft of femur is aligned with anterior half of the lateral condyle
    • There is a anatomic axis 9 degrees of valgus (7 – 11 degrees)
    • On axial section teh distal femur is trapezoidal in shape which has implications for implant placement and the prominence of screws
  • Mechanism of injury
    • High-energy (significantly displaced)
      • Motorvehicle accident
      • Fall from height
    • Low-energy (less displacement)
      • Fall from standing height on flexed knee (in weakened bone)
  • Deforming forces
    • Shortening is caused by the quadriceps and hamstrings
    • Apex posterior angulation and posterior displacement is caused by gastrocnemius (can obstruct the popliteal vessels)
    • Varus angulation caused by hip adductors
  • Associated injuries
  • Signs and symptoms
    • Inability to bear weight
    • Pain of the distal femur
      • Worse with knee movement
    • Deformity of the distal thigh and knee
  • Physical examination
    • Tenderness
    • Swelling
    • Ecchymosis
    • Neurovascular examination (potential injury to the popliteal artery)
  • Investigations
    • X-ray: AP and lateral views + joint above and below
      • Double density on AP (Hoffa fragment)
      • Paradoxical notch view on AP (articular fragment in recurvatum)
    • CT-scan: to demonstrate intra-articular involvement, coronally oriented hoffa fragment and pre-operative planning
      • Hoffa fracture in the coronal plane
      • Separate osteochondral fragments int he area of the intervondylar notch
    • Ankle-brachial index (ABI): to rule out vascular injury
    • CT angiogram: Indicated if ABI is < 0.9
  • Hoffa fragment
    • A Hoffa fragment is an intra-articular distal femoral fracture in the coronal plane
    • It occurs in 38% of distal femur fractures and is easy to miss on plain radiograph (missed 31% of the time)
    • Affects the lateral condyle more than the medial condyle (80%)
  • Treatment of distal femur fracture
    • Resuscitation
    • Splinting with a bohler-brown splint or thomas splint with a flexion device to minimize compression of the popliteal vessels
    • External fixation
    • Open reduction internal fixation (ORIF)
    • Closed reduction and intramedullary fixation (IMN)
    • Non-operative treatment with a long-leg cast followed by hinged knee brace (rare)
    • Distal femur Arthroplasty
    • Early range of motion exercises to prevent stiffness
    • Non-weight bearing until evidence of fracture union
  • Open reduction and internal fixation
    • Anterior to posterior screw for Hoffa fragment
    • Dynamic condylar screw (DCS) plate
    • Lateral locked distal femur plates (31% rate of non-union)
    • Intramedullary nail
  • Indications for external fixation
    • Temporary measure
      • Unstable polytrauma
      • Extensive soft tissue damage
      • Contamination requiring multiple debridement
    • Definitive measure
      • Severe open and/or comminuted fracture
      • Unstable for surgery
  • Indications for arthroplasty
    • Pre-existing osteoarthritis with amenable fracture pattern
  • Indications for non-operative management (rare)
    • Medical contraindication to surgery
    • Non-ambulatory
    • Non-displaced fracture
    • Impacted, stable fracture
    • Non-reconstructable fracture
    • Severe osteopaenia
    • Lack of experienced operative treatment, instruments or facilities
  • Early complications of the distal femur fracture
  • Late complications of distal femur fracture
    • Knee pain and/or stiffness
    • Post-traumatic osteoarthritis
    • Malunion
    • Non-union
    • Implant failure
Reference Intervals
Biochemistry
ACTHP: <80 ng/L
ALTP: 5–35 U/L
AlbuminP: 35–50 g/L
AldosteroneP: 100–500 pmol/L
Alk. phosphataseP: 30–130 U/L
α-AmylaseP: 0–180 IU/dL
α-FetoproteinS: <10 kU/L
Angiotensin IIP: 5–35 pmol/L
ADHP: 0.9–4.6 pmol/L
ASTP: 5–35 U/L
BicarbonateP: 24–30 mmol/L
BilirubinP: 3–17 μmol/L
BNPP: <50 ng/L
CRPP: <10 mg/L
CalcitoninP: <0.1 mcg/L
Calcium (ionized)P: 1.0–1.25 mmol/L
Calcium (total)P: 2.12–2.60 mmol/L
ChlorideP: 95–105 mmol/L
CholesterolP: <5.0 mmol/L
VLDLP: 0.128–0.645 mmol/L
LDLP: <2.0 mmol/L
HDLP: 0.9–1.93 mmol/L
Cortisol AMP: 450–700 nmol/L
Cortisol MidnightP: 80–280 nmol/L
CK ♂P: 25–195 U/L
CK ♀P: 25–170 U/L
CreatinineP: 70–100 μmol/L
FerritinP: 12–200 mcg/L
FolateS: 2.1 mcg/L
FSHP: 2–8 U/L ♂; >25 menopause
GGT ♂P: 11–51 U/L
GGT ♀P: 7–33 U/L
Glucose (fasting)P: 3.5–5.5 mmol/L
Growth hormoneP: <20 mu/L
HbA1C (DCCT)B: 4–6%
HbA1C (IFCC)B: 20–42 mmol/mol
Iron ♂S: 14–31 μmol/L
Iron ♀S: 11–30 μmol/L
Lactate (venous)P: 0.6–2.4 mmol/L
Lactate (arterial)P: 0.6–1.8 mmol/L
LDHP: 70–250 U/L
LHP: 3–16 U/L
MagnesiumP: 0.75–1.05 mmol/L
OsmolalityP: 278–305 mosmol/kg
PTHP: 0.8–8.5 pmol/L
PotassiumP: 3.5–5.3 mmol/L
Prolactin ♂P: <450 U/L
Prolactin ♀P: <600 U/L
PSAP: 0–4 mcg/mL
Protein (total)P: 60–80 g/L
Red cell folateB: 0.36–1.44 μmol/L
Renin (erect)P: 2.8–4.5 pmol/mL/h
Renin (recumbent)P: 1.1–2.7 pmol/mL/h
SodiumP: 135–145 mmol/L
TBGP: 7–17 mg/L
TSHP: 0.5–4.2 mU/L
T4P: 70–140 nmol/L
Free T4P: 9–22 pmol/L
TIBCS: 54–75 μmol/L
TriglyceridesP: 0.50–2.3 mmol/L
T3P: 1.2–3.0 nmol/L
Troponin TP: <0.1 mcg/L
Urate ♂P: 210–480 μmol/L
Urate ♀P: 150–390 μmol/L
UreaP: 2.5–6.7 mmol/L
Vitamin B12S: 0.13–0.68 nmol/L
Vitamin DS: 50 nmol/L
Arterial Blood Gases
pH7.35–7.45
PaCO₂4.7–6.0 kPa
PaO₂>10.6 kPa
Base excess±2 mmol/L
Urine
Cortisol (free)<280 nmol/24h
Hydroxyindole acetic acid16–73 μmol/24h
Hydroxymethylmandelic acid16–48 μmol/24h
Metanephrines0.03–0.69 μmol/mmol cr.
Osmolality350–1000 mosmol/kg
17-Oxogenic steroids ♂28–30 μmol/24h
17-Oxogenic steroids ♀21–66 μmol/24h
17-Oxosteroids ♂17–76 μmol/24h
17-Oxosteroids ♀14–59 μmol/24h
Phosphate (inorganic)15–50 mmol/24h
Potassium14–120 mmol/24h
Protein<150 mg/24h
Protein/creatinine ratio<3 mg/mmol
Sodium100–250 mmol/24h
Haematology
WCC4.0–11.0 ×10⁹/L
RBC ♂4.5–6.5 ×10¹²/L
RBC ♀3.9–5.6 ×10¹²/L
Hb ♂130–180 g/L
Hb ♀115–160 g/L
PCV ♂0.4–0.54 L/L
PCV ♀0.37–0.47 L/L
MCV76–96 fL
MCH27–32 pg
MCHC300–360 g/L
RDW11.6–14.6%
Neutrophils2.0–7.5 ×10⁹/L (40–75%)
Lymphocytes1.0–4.5 ×10⁹/L (20–45%)
Eosinophils0.04–0.44 ×10⁹/L (1–6%)
Basophils0–0.10 ×10⁹/L (0–1%)
Monocytes0.2–0.8 ×10⁹/L (2–10%)
Platelets150–400 ×10⁹/L
Reticulocytes0.8–2.0% / 25–100 ×10⁹/L
Prothrombin time10–14 s
APTT35–45 s
Paediatric
Pulse Rate (bpm)
Neonate140–160
Infant <1yr120–140
1–5 years110–130
5–12 years80–120
>12 years70–100
Respiratory Rate (tachypnoea)
0–2 months≥60/min
2–12 months≥50/min
1–5 years≥40/min
>5 years≥30/min
Blood Pressure (mmHg)
Term65/45
1 year75/50
4 years85/60
8 years95/65
10 years100/70
Weight Formulas
3–12 months(a + 9)/2 kg
1–6 years2a + 8 kg
>6 years(7a − 5)/2 kg
Haemoglobin (g/dL)
Term newborn13–20
1 month11–18
2 months10–15
1–2 years10–13
>2 years11–14
MUAC (6 months–5 years)
Obese>17.5 cm
Normal13.5–17.4 cm
At risk12.5–13.4 cm
Moderate malnutrition11.5–12.4 cm
Severe malnutrition<11.5 cm
Developmental Milestones
Social smile1.5 months
Head control4 months
Sits unsupported7 months
Crawls10 months
Stands unsupported10–12 months
Walks12–13 months
Talks18 months
CSF WBC (/mm³)
Term newborn0–25
>2 weeks0–5
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