Erythema Multiforme This is a common reaction pattern of blood vessels in the dermis with secondary epidermal changes. It is an acute, self-limited Type IV hypersensitivity reaction. It manifests clinically as characteristic erythematous iris-shaped papular and vesiculo-bullous lesions (Bullseye). The…
Overview Basal cell carcinoma (BCC) is a non-melanoma (keratinocyte), epithelial skin cancer arising from the basal cells (small, round cells in lower layer of dermis). Is the most common malignant skin tumor in humans. More common in males (M:F ~2:1)…
Overview Cutaneous squamous cell carcinoma (cSCC) is a non-melanoma (keratinocyte), epithelial skin cancer derived from the malignant transformation of normal epidermal keratinocytes (produce keratin – horny protein that makes up skin, hair, nails). It typically appears on sun-exposed skin, and…
Gestational Pemphigoid (Pemphigoid gestationis) This refers to a bullous pemphigoid-like dermatosis that occurs in pregnancy, usually during the 2nd and 3rd trimesters. Aetiology is unknown, but most likely immunological. BP180 protein, which is identified in bullous pemphigoid, is also found…
Overview Bullies pemphigoid is a chronic, inflammatory, sub-epidermal, autoimmune blistering disease. It is the most common form of autoimmune sub-epidermal blistering disease. More prevalent among the elderly, occurring equally in males and females. Pathophysiology Bullous pemphigoid results from the attack…
Overview Urticaria is an inflammatory skin disorder, resulting in formation of well circumscribed, erythematous, edematous and pruritic plaques called wheals/ hives. ****It may occur with or without angioedema. Can be classified as acute (<6 weeks) or chronic (>6 weeks). Etiology…
Overview Dermatology can be defined as the study of both normal and abnormal skin, and associated structures such as hair, nails, and oral and genital mucous membranes. Dermatological History Fitzpatrick skin type and scoring Skin type and score Typical features…
Overview *Revisit embryology of bone! Pediatric vs adult bone Pediatric Adult Higher water content Lower water content Lower mineral content Higher mineral content Less brittle (more elastic) More brittle Higher strain-to-failure Lower strain-to-failure Stronger in tension than compression Stronger in…
Introduction Meckel’s diverticulum is a blind out-pouching of anti-mesenteric aspect of the middle-to-distal ileum. It is a true diverticulum of the gastrointestinal duct containing all layers of the bowel walls and its own artery. It is named after Johann Friedrick…
Since I was a little girl, I have always been on the lookout for magic. When I was 5, I remember thinking I saw magic behind my eyelids; bright flashes of colour and mesmerising patterns when I closed my eyes…