Updated on November 12, 2024 Describe the mechanism of Type II hypersensitivity Opsonization and phagocytosis Opsonized RBCs and platelets become targets for phagocytosis by neutrophils and macrophages. Phagocytes express Fc receptors for IgG and Breakdown products of C3 Opsonized cells are eliminated in the spleen, and this is why splenectomy is beneficial in autoimmune thrombocytopenia...