Outline 5 examples of type I hypersensitivity related conditions Allergic rhinitis/sinusitis Allergic urticaria Non-complement related Angioedema (Allergic angioedema) Food Allergy Bronchial Asthma Insect Bites Anaphylaxis Describe in details the mechanism of Hypersensitivity Type I reaction Sensitization APC (Macrophage, DC) present allergen Activated Th2 secretes IL-4, IL-5, IL-13 B-cells Class switching to IgE IgE binds to…...
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