Nursery Examination

Last updated: March 31, 2026

Overview

The nursery exam is done in the nursery or NICU within 24 hours of birth to identify any abnormalities or anomalies that may impact the infant’s current or future well-being.

The presence of one or two isolated anomalies is not unusual. It is the sequences or constellations of anomalies that are associated with various congenital illnesses.

General Examination

Introduce yourself, explain, get consent, and sanitize. Start the exam with a general observation.

  • Modified Pediatric GCS/ AVPU
  • How is the baby lying in bed (attitude)
  • Look for gross anomalies without touching
  • Skin colour
  • Breathing quality
  • Anthropometric measurements

Modified Pediatric GCS

Eye opening

Eye openingScore
Spontaneous4
To speech3
To pain only2
No response1

Best verbal response

Best verbal responseScore
Coos and babbles5
Irritable cries4
Cries to pain3
Moans to pain2
No response1

Best motor response

Best motor responseScore
Moves spontaneously and purposefully6
Withdraws to touch5
Withdraws in response in pain4
Abnormal flexion to pain3
Abnormal extension to pain2
No response1

Vitals

Vital signReference range
Heart rate120-160 bpm
Respirations30-60 rpm
Blood pressure50-70 mmHg systolic
Temperature36.1 – 37.9 C

Simplified comparison based on typical Ballard’s Score results for preterm and term neonates:

CharacteristicPreterm Neonate (Premature)Term Neonate
Skin TextureUsually smoother and less mature skinSkin is typically well-textured
LanugoAbundant lanugo (fine hair) is often presentLanugo may be sparse or absent
Plantar SurfaceFewer creases on the soleMore defined creases on the sole
Breast DevelopmentLess developed breasts (both genders)More developed breasts (if female)
Eyes and EarEyelids may be fused, soft earsLids open, firm ears
Genitalia DevelopmentMale genitalia may be less developed, female genitalia less matureMale and female genitalia are typically fully developed
Physical MaturityLess subcutaneous fat, less muscle toneTypically good subcutaneous fat and muscle tone

Examination of the Skin

The skin of neonates is normally pink. Note that babies may have blue or purple extremities immediately after delivery.

Skin findingDescription
JaundiceAbnormal in the first 24 hours. Could be due to a hemolytic process, Rh isoimmunization, congenital hepatitis, etc.
PallorSuggests acute or chronic blood loss, or acidosis
CyanosisSuggests poor cardiac output or a cold baby
PlethoraSuggests polycythemia
TextureCrackling or peeling of skin is typical of post-term infants
EdemaDescribe whether it is generalized or localized
Bruising or petechiaeSuggests birth trauma or bleeding disorder
Cutis marmorataLacing or mottling of the skin because babies have poor temperature regulation. Capillaries can be seen through the skin. This is temporary
Vernix caseosaCurdy, greasy (’cheesy’) white substance on term babies at delivery. This is normal
Erythema toxicumMigratory pink, maculopapular rash seen after the first 24 hours. It is the immune system’s way of asserting itself. Normal and goes away after a few weeks
Staphylococcal scalded skin syndrome (SSSS)Diffuse red rash, burn-like with denuded skin and Nikolsky sign. Requires broad-spectrum antibiotics and fluid STAT
Subcutaneous fat necrosisErythematous, indurated, circumscribed nodules. May be idiopathic or due to birth trauma. Does not require treatment, but calcium is checked periodically.
Capillary hemangiomaRed papules on the head or face. Does not usually present within the first 23 hours. It can grow in size, but involutes later
Port-wine stainFlat red birthmark (patch). Unilateral facial port-wine stains are associated with Sturge-Weber syndrome
Mongolian spotsBlackish blue spots on the buttocks. These are clearly demarcated, unlike bruises.
Cafe-au-lait spotsLight brown spots. ≤ 3 is normal in a white infant. ≤ 5 is normal in a black infant. ≥ 6 is associated with various diseases, including neurofibromatosis type 1 and tuberous sclerosis

Examination of the Head

Support the head by putting your hand behind the occiput. Look for scalp abnormalities. Gently palpate fontanelles. 6 fontanelles

FontanelleApproximate width
Anterior fontanele1-4 cm
Posterior fontanelle< 1cm

Scalp layers

Some scalp findings

Scalp findingDescription
Caput succedaneum“Cone head” swelling of the head that crosses suture lines since it is superficial to the periosteum (between the scalp and subgaleal aponeurosis). It is common in babies delivered by SVD (due to pressure). It resolves within a few days
CephalohematomaSwelling of the head limited by suture lines since blood collects between the skull bone and periosteum. May follow with jaundice and may be associated with an underlying linear skull fracture
Subgaleal hemorrhageA potentially massive bleed that is noted as a fluctuant, boggy mass with superficial skin bruising. It may obscure suture lines since it is superficial to the periosteum. It is associated with vacuum-assisted delivery (90% of babies). Monitor for hypotension or tachycardia since the scalp can hold a lot of blood, causing the baby to bleed out)
MeningoceleUsually located in the midline in the occipital region. Associated with underlying bony defects
Third fontanelleUsually along the sagittal suture. Associated with various cogenital syndromes, especially Down syndrome
Bulging fontanelleA sign of raised ICP suggestive of meningitis or encephalitis

Examination of the Eyes

Babies are born with 20/400 vision.

Eye findings

Eye findingsDescription
Subconjunctival hemorrhageThese are common and are due to the stress of birth. Mother may also have them
Coloboma“Latch-key” defect of the iris associated with CHARGE syndrome
AniridiaSevere hypoplasia or absence of the iris. Has visual implication sand is associated with WAGR syndrome
Hyphaema or cloudy corneaCorneal opacities require an ophthalmology consult
Leukocoria (white reflex)This needs immediate attention (ophthalmology consult) since it suggests retinoblastoma, cataract or glaucoma
SecretionsSuggests conjunctivitis. Can order TORCH titres from the mother for congenital infections.

Examination of the Ears

Malformed or malpositioned ears are associated with various congenital anomalies.

Ear findings

Ear findingsDescription
MicrotiaThis is a severely malformed ear. A CT scan should be ordered to see if the inner ear is developed
Preauricular pits and tagsThese have a familial pattern and may be benign. They may also be associated with genitourinary defects or hearing abnormalities. Tags may be associated with a cleft palate

Examination of the Nose

Examine the shape of the nose

Examine the patency of the nares – this is important because babies are obligate nose breathers.

Look for steam collection on a chilled reflex hammer placed under the baby’s nose. A light can also be shone, or an attempt to insert a nasogastric tube into the nares can be performed.

Nose findings

Nose findingsDescription
Abnormally flattened noseDue to intrauterine compression
Flaring of the nasal alaeSeen in respiratory distress
Choanal atresiaThis is the ‘A’ in CHARGE syndrome. The baby becomes cyanotic during feeding, but is relieved when crying (since they breathe through the mouth)
Nasal secretions“Snuffles” are seen in congenital syphilis

Examination of the Mouth and Throat

Examine the mouth using a gloved index finger.

Examine the sucking and rooting reflexes.

Examine the tongue

Examine the palate.

Examine the mandible; if the chin is small, the mandible is small.

Mouth and throat findings

Mouth and throat findingsDescription
Flat philtrum and thin lipsSeen in fetal alcohol syndrome
Natal teethIf present, they may be removed due to the risk of aspiration
Epstein pearls (epithelial retention cysts)Seen along the gum margins. Usually resolves in a month
MacroglossiaTrue macroglossia is seen in Beckwith-Wiedemann syndrome, congenital hypothyroidism and micropolysaccharidosis. Apparent macroglossia is seen in Down syndrome due to a small mouth
AnkyloglossiaAn unusually short frenulum that reduces the mobility of the tongue
Cleft palate
MicrognathiaA small mandible. Associated with multiple syndromes, including Pierre-Robin sequence
Subglottic hemangiomaThis may block the airway

Examination of the Neck

Look for webbing and masses.

Masses should be identified early since they can become infected.

Neck findings

Neck findingsDescription
WebbingExcessive nuchal skin. Seen in Turner’s and Noonan’s syndrome
Midline neck massMay be a thyroglossal duct cyst (oves with swallowing or tongue protrusion)
Neck mass anterior to SCM (lateral to midline)May be a branchial cleft cyst
Neck mass posterior to SCMMay be a cystic hygroma
Congenital torticollisResistance is felt when turning the baby’s head to the opposite direction

Examination of the Chest

Lungs

  • Bones
    • Fractures, especially clavicular fractures, occur in babies born during traumatic or surgical deliveries
  • Air entry
    • Should be bilateral
    • Unilateral breath sounds suggest a pneumothorax
  • Breath sounds
    • Periodic breathing
    • Grunting
    • Added sounds: stridor or wheeze
    • Absent on the left: pneumothorax or congenital diaphragmatic hernia. The point of maximal cardiac impulse is displaced in the case of a diaphragmatic hernia.
    • Tachypnea (>60 RPM) or adventitious breath sounds suggest respiratory distress
    • Decreased breath sounds suggest hyaline membrane disease
  • Breast hypertrophy
    • This is a normal response to circulating maternal hormones
    • Some milk may even be produced
  • Supernumerary nipples
    • Looks like moles
    • They can be surgically corrected later
  • Pectus carinatum
    • A bulging sternum
  • Pectus excavatum
    • An indented sternum
    • Can compress the mediastinum if severe enough

Heart

The heart rate should be between 120 and 160 bpm.

Palpate the peripheral pulses on all 4 extremities

  • Murmurs
    • Murmurs are normal in the first few hours after birth
    • Murmurs and cyanosis suggest a congenital heart defect
    • Muffled heart sounds suggest pneumomediastinum
  • The point of maximal impulse (PMI)

Examination of the Abdomen

Assess the shape of the abdomen.

Inspect and auscultate first before palpating or percussing the abdomen.

  • Scaphoid abdomen
  • Distended abdomen
    • Excess gas
    • Mass
    • Peritoneal fluid
  • The umbilical stump
    • It should not be bleeding or harbour signs of infection
  • Bowel sounds
  • Herniaa
    • Umbilical hernia
    • Omphalocele appears as a midline defect with abdominal contents covered by the peritoneal membrane. It is seen in Beckwith-Wiedemann syndrome
    • Gastroschisis appears as a defect lateral to the midline with abdominal contents lacking a peritoneal membrane covering. It is usually diagnosed in utero. There is an increased risk of malrotation and ischemia
  • Polycystic kidneys
    • This is the most common true abdominal mass in neonates
  • Palpate the liver and abdominal mass

Examination of the Genitals and Anus

Check for patency of the anus, position of the urethral orifice, descension of the testicles

  • Imperforate anus
    • Associated with the VACTREL complex
  • Hypospadias
    • The urethral orifice is displaced ventrally
  • Epispadias
    • The urethral orifice is displaced dorsally
  • Undescended testes
  • Clitoral enlargement
    • Temporary enlargement due to maternal hormones
  • Enlarged bladder
    • Suggests posterior urethral valves. This should be confirmed using an ultrasound

Examination of the Extremities

Are there ten fingers and 10 toes?

Check for developmental dysplasia of the hip (DDH), spinal alignment, webbing, fusion and polydactyly of the fingers and toes.

Ensure there are no absent bones, e.g., the radius in radial clubhand

  • Positive Ortolani and Barlow manoeuvres
    • “Click” or “thump” suggests developmental dysplasia of the hip
  • Webbing
    • Both bones are present, but their skin is fused
  • Fusion (syndactyly)
    • Both bones are fused
  • Congenital absence of the radius
    • Radius clubhand
  • Congenital absence of the fibula
    • Fibular hemimelia
  • Club foot

Neurological Examination

Test the newborn reflexes

  • Moro (”startle”) reflex
    • The baby should abduct the arm at the shoulder and extend at the elbow with spread fingers
    • Disappears at 3 months
    • Abnormal in Erb’s palsy
  • Palmar grasp reflex
    • The baby grasps a finger in its palm
    • Disappears at 4 months
    • Abnormal in Klumpke’s palsy
  • Sucking reflex
    • The baby will suck a gloved finger or a nipple when placed in the mouth.
  • Rooting reflex
    • The baby turns the head towards the side where the cheek is touched
  • Tonic neck reflex
    • The baby assumes a “fencing position” on the opposite side when the neck is passively turned on one side
  • Babinski reflex
    • Upgoing (extensor) plantar
    • Normal in babies
    • Abnormal past 1/2 years of age.

Reference Intervals
Biochemistry
ACTHP: <80 ng/L
ALTP: 5–35 U/L
AlbuminP: 35–50 g/L
AldosteroneP: 100–500 pmol/L
Alk. phosphataseP: 30–130 U/L
α-AmylaseP: 0–180 IU/dL
α-FetoproteinS: <10 kU/L
Angiotensin IIP: 5–35 pmol/L
ADHP: 0.9–4.6 pmol/L
ASTP: 5–35 U/L
BicarbonateP: 24–30 mmol/L
BilirubinP: 3–17 μmol/L
BNPP: <50 ng/L
CRPP: <10 mg/L
CalcitoninP: <0.1 mcg/L
Calcium (ionized)P: 1.0–1.25 mmol/L
Calcium (total)P: 2.12–2.60 mmol/L
ChlorideP: 95–105 mmol/L
CholesterolP: <5.0 mmol/L
VLDLP: 0.128–0.645 mmol/L
LDLP: <2.0 mmol/L
HDLP: 0.9–1.93 mmol/L
Cortisol AMP: 450–700 nmol/L
Cortisol MidnightP: 80–280 nmol/L
CK ♂P: 25–195 U/L
CK ♀P: 25–170 U/L
CreatinineP: 70–100 μmol/L
FerritinP: 12–200 mcg/L
FolateS: 2.1 mcg/L
FSHP: 2–8 U/L ♂; >25 menopause
GGT ♂P: 11–51 U/L
GGT ♀P: 7–33 U/L
Glucose (fasting)P: 3.5–5.5 mmol/L
Growth hormoneP: <20 mu/L
HbA1C (DCCT)B: 4–6%
HbA1C (IFCC)B: 20–42 mmol/mol
Iron ♂S: 14–31 μmol/L
Iron ♀S: 11–30 μmol/L
Lactate (venous)P: 0.6–2.4 mmol/L
Lactate (arterial)P: 0.6–1.8 mmol/L
LDHP: 70–250 U/L
LHP: 3–16 U/L
MagnesiumP: 0.75–1.05 mmol/L
OsmolalityP: 278–305 mosmol/kg
PTHP: 0.8–8.5 pmol/L
PotassiumP: 3.5–5.3 mmol/L
Prolactin ♂P: <450 U/L
Prolactin ♀P: <600 U/L
PSAP: 0–4 mcg/mL
Protein (total)P: 60–80 g/L
Red cell folateB: 0.36–1.44 μmol/L
Renin (erect)P: 2.8–4.5 pmol/mL/h
Renin (recumbent)P: 1.1–2.7 pmol/mL/h
SodiumP: 135–145 mmol/L
TBGP: 7–17 mg/L
TSHP: 0.5–4.2 mU/L
T4P: 70–140 nmol/L
Free T4P: 9–22 pmol/L
TIBCS: 54–75 μmol/L
TriglyceridesP: 0.50–2.3 mmol/L
T3P: 1.2–3.0 nmol/L
Troponin TP: <0.1 mcg/L
Urate ♂P: 210–480 μmol/L
Urate ♀P: 150–390 μmol/L
UreaP: 2.5–6.7 mmol/L
Vitamin B12S: 0.13–0.68 nmol/L
Vitamin DS: 50 nmol/L
Arterial Blood Gases
pH7.35–7.45
PaCO₂4.7–6.0 kPa
PaO₂>10.6 kPa
Base excess±2 mmol/L
Urine
Cortisol (free)<280 nmol/24h
Hydroxyindole acetic acid16–73 μmol/24h
Hydroxymethylmandelic acid16–48 μmol/24h
Metanephrines0.03–0.69 μmol/mmol cr.
Osmolality350–1000 mosmol/kg
17-Oxogenic steroids ♂28–30 μmol/24h
17-Oxogenic steroids ♀21–66 μmol/24h
17-Oxosteroids ♂17–76 μmol/24h
17-Oxosteroids ♀14–59 μmol/24h
Phosphate (inorganic)15–50 mmol/24h
Potassium14–120 mmol/24h
Protein<150 mg/24h
Protein/creatinine ratio<3 mg/mmol
Sodium100–250 mmol/24h
Haematology
WCC4.0–11.0 ×10⁹/L
RBC ♂4.5–6.5 ×10¹²/L
RBC ♀3.9–5.6 ×10¹²/L
Hb ♂130–180 g/L
Hb ♀115–160 g/L
PCV ♂0.4–0.54 L/L
PCV ♀0.37–0.47 L/L
MCV76–96 fL
MCH27–32 pg
MCHC300–360 g/L
RDW11.6–14.6%
Neutrophils2.0–7.5 ×10⁹/L (40–75%)
Lymphocytes1.0–4.5 ×10⁹/L (20–45%)
Eosinophils0.04–0.44 ×10⁹/L (1–6%)
Basophils0–0.10 ×10⁹/L (0–1%)
Monocytes0.2–0.8 ×10⁹/L (2–10%)
Platelets150–400 ×10⁹/L
Reticulocytes0.8–2.0% / 25–100 ×10⁹/L
Prothrombin time10–14 s
APTT35–45 s
Paediatric
Pulse Rate (bpm)
Neonate140–160
Infant <1yr120–140
1–5 years110–130
5–12 years80–120
>12 years70–100
Respiratory Rate (tachypnoea)
0–2 months≥60/min
2–12 months≥50/min
1–5 years≥40/min
>5 years≥30/min
Blood Pressure (mmHg)
Term65/45
1 year75/50
4 years85/60
8 years95/65
10 years100/70
Weight Formulas
3–12 months(a + 9)/2 kg
1–6 years2a + 8 kg
>6 years(7a − 5)/2 kg
Haemoglobin (g/dL)
Term newborn13–20
1 month11–18
2 months10–15
1–2 years10–13
>2 years11–14
MUAC (6 months–5 years)
Obese>17.5 cm
Normal13.5–17.4 cm
At risk12.5–13.4 cm
Moderate malnutrition11.5–12.4 cm
Severe malnutrition<11.5 cm
Developmental Milestones
Social smile1.5 months
Head control4 months
Sits unsupported7 months
Crawls10 months
Stands unsupported10–12 months
Walks12–13 months
Talks18 months
CSF WBC (/mm³)
Term newborn0–25
>2 weeks0–5
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