Internal Medicine Comprehensive Quiz
Test your knowledge on Internal Medicine by answering the questions provided in this quiz.
2.
Which drug is unlikely to cause toxic epidermal necrolysis?
3.
Which of the following is the most common cause of lower GI bleed under age of 50?
5.
All of the following are indications for urgent endoscopy for upper gastrointestinal bleeding except:
7.
Which modality is recommended for further workup of demyelinating disease?
9.
A 17 year old man attends the local sexual health clinic. He has developed a large, keratinised genital wart on the shaft of his penis. This has been around for 3 months but he has been too embarrassed to present before now. What is the most appropriate initial management?
10.
A 45 year old male presents with sudden onset right sided weakness and slurred speech. Which artery is most likely affected?
11.
Which of the following infectious organisms is most likely to cause relative bradycardia during a febrile event?
12.
The most common subtype of Non-Hodgkin lymphoma in African children is?
13.
Select the false statement regarding factors affecting rate of iron absorption:
14.
Shoulder pain is a recognised feature of:
15.
On what chromosome is the sickle cell gene point mutation?
16.
A patient suffered from nephrogenic systemic fibrosis (NSF) after gadolinium administration for an MRI. Which of the following is the strongest risk factors for NSF?
17.
The following are common complications of liver cirrhosis EXCEPT:
18.
In the pancreas, which are the cells that secrete insulin, decrease the blood levels of glucose:
19.
Which of the following is not a first-line anti hypertensive drug?
20.
The enzyme amylase is principally responsible for the breakdown of which one of the following?
21.
Which of the following coagulation factors is not involved in the intrinsic pathway?
22.
A 45-year-old woman is admitted to the emergency room after a first episode of witnessed generalized tonic-clonic seizure. She is administered lorazepam 2mg with cessation of seizure activity. All of the following are likely possible causes of her seizure EXCEPT?
23.
Ineffective erythropoiesis is characteristic of which one:
24.
Which of the following is the gene involved in 95% of cases of polycythemia vera?
25.
Which of the following gastrointestinal conditions is characterized by non-inflammatory visceral pain?
26.
Which of the following imaging modalities evaluates thyroid function?
27.
The following are examples of supraventricular arrhythmias except:
28.
Laxatives are used in management of constipation. Which of the following laxatives is incorrectly matched with its class?
29.
CD20 is a phosphoprotein generally expressed in?
30.
Leads aVR, aVL, and aVF are known as:
31.
Which of the following viruses is the common cause of sickle cell aplastic crisis?
32.
Which of the following drugs is a first-line therapy for the treatment of acute exacerbations of chronic obstructive pulmonary disease (COPD)?
33.
Romanowsky stains are used universally for routine staining of blood films. Which of the following is not among them?
34.
Erythema Nodosum is an example of?
35.
The strongest risk factor for development of asthma is?
36.
Which of the following regarding hemostasis is false?
37.
A 60-year-old female patient presented to the clinic with insidious onset of rectal bleeding and frequent stools with mucoid discharge. Physical exam revealed mild abdominal tenderness in the lower left quadrant. On serological testing pANCA (perinuclear antineutrophil cytoplasmic antibodies) was found to be positive. Histologically, the inflammation was found to be limited to the mucosa and submucosa, with continuous inflammation extending proximally from the rectum seen on colonoscopy. What is the most likely diagnosis?
38.
What is the primary mechanism of action of statin medications in the management of hyperlipidemia?
39.
Which of the following is the most specific indicator of CKD progression?
40.
Malabsorption due to mucosal intestinal defects is seen in:
41.
Geographic tongue is seen in:
42.
The posterior pituitary stores and releases:
43.
Which of the following is not a feature of organophosphate poisoning?
44.
The endocrine gland responsible for the body's circadian rhythm is the:
45.
A 36-year-old woman with AIDS and a CD4 of 34/uL presents with odynopahia, progressive dysphagia, and daily fevers with an unintentional weight loss of 10 kg. She has been treated with clotrimazole lozenges without relief. On exam she has a BMI of 16 and a weight of 46 kg. Her temperature is 38.2 C. There is no thrush on oral examination. She undergoes an esophagogastroduodenoscopy (EGD) which reveals serpiginous ulcers in the distal esophagus without vesicles. There are no yellow plaques. Biopsies of the lesions show intranuclear and intracytoplasmic inclusions in large endothelial cells and fibroblasts. What is the best treatment for this patient’s esophagitis?
46.
Which GIT hormone stimulates enzyme rich pancreatic juice secretion?
47.
The first-line therapy for Graves' disease is:
48.
Which of the following is not a vitamin K dependent factor:
50.
A 68-year-old man with a history of myocardial infarction and congestive heart failure is comfortable at rest. However, when walking to his car he develops dyspnea, fatigue, and sometimes palpitations. He must rest for several minutes before these symptoms resolve. Which is his New York Heart Association classification?
51.
A 37 yo male presents with severe fatigue, frequent nose bleeds, and gingival masses. The abnormal cells seen in the blood smear show tissue paper nuclei. What is the diagnosis?
53.
A 19 year old man presents to the endocrinology clinic. He has a short stature, a history of delayed puberty, color blindness, and anosmia. He is diagnosed with Kallman syndrome. Which of the following is the most appropriate treatment?
54.
Criteria for diagnosis of rheumatoid arthritis include the following except:
55.
The following are parts of the nail. Which one is not?
57.
A 35-year-old woman presents with new headache. MRI revelas a pituitary lesion. Which of the following laboratory findings is suggestive of a functional pituitary adenoma?
58.
A 25 year old male presents with painless hemtauria. His family history is significant for hematuria and hearing loss. What is the most likely diagnosis?
59.
A 55-year old male has been experiencing heartburn, regurgitation, dysphasia and hoarseness of voice. Esophagogastroduodenoscopy showed esophagitis. Which of the following is not a risk factor associated with the disease?
61.
Which of the following is not a risk factor for basal cell carcinoma?
62.
Which of the following STIs can be prevented through vaccination?
63.
What is the laboratory definition of overt hyperthyroidism?
64.
A 14 year old female student presents with a three day history of a 1cm, golden crusted lesion on the border of her lower lip. What is the most appropriate management?
65.
Which of the following is an indicator of good prognosis for pre-B childhood ALL?
66.
Which of the following hematologic disorders is characterized by the presence of the Philadelphia chromosome (t(9;22) translocation)?
67.
The following are used to treat hyperkalemia except?
68.
Which of the following statements regarding the use of triptan agonists in the treatment of migraine is INCORRECT?
69.
Regarding pemphigus vulgaris, which is false?
71.
In achalasia, the most effective long term therapy is:
73.
The following are types of human hair lice except:
74.
Skin lesions can be classified as primary or secondary. Which of the following is a secondary lesion?
76.
All of the following are effective in treating pure tension-type headaches except?
77.
Which of the following is a non-fibrin specific fibrinolytic agent?
78.
A mother brought her child to the pediatric endocrinology clinic. He had a distended abdomen and macroglossia, prolonged jaundice, was lethargic and feeding poorly, and had a mass protruding from his umbilicus. What is the most likely diagnosis?
79.
Opportunistic CNS infections in patients with HIV include all of the following except?
80.
The major enzyme responsible for protein digestion in the small bowel is:
81.
Oral lesions of syphilis that are highly infectious are:
82.
Presentation with acute monoarthritis suggests the possibility of the following except:
83.
Salmonella food poisoning is common due to:
84.
A 44-year-old woman presents with new ulcers on both her lower extremities. They began as pustules then turned into ulcers with necrotic violaceous edges and a peripheral erythematous halo. She has a history of ulcerative colitis and DVT diagnosed 4 months ago, for which she is taking warfarin. Which is the most likely cause of her ulcers?
85.
Pulsus paradoxus may be observed in the following conditions except:
86.
Which of the following is not a criterion for diagnosis of metabolic syndrome?
87.
Which of the following is a long term complication of therapy with cytotoxic drugs:
88.
A 29-year-old male presented with complaints of prolonged diarrhoea with abdominal pain, weight loss and generalised fatiguability. On physical examination he was found to have a low-grade fever, diffuse abdominal tenderness, and a palpable mass in the right lower quadrant. Perineal examination revealed presence of skin tags around the anus. Oral examination revealed presence of aphthous ulcers. Biopsy findings included transmural inflammation and presence of non-caseating granulomas. ASCA (anti-saccaromyces cerevisiae antibodies) was positive. What is the most likely diagnosis?
89.
Deficiency of factor XI leads to the following condition:
90.
The following is false regarding HIV virus:
91.
Which of the following is the most common inherited bleeding disorder?
93.
Which is not a Vitamin K dependent clotting factor produced by the liver?
94.
The three major anatomical constrictions within the adult esophagus include all of the following except:
95.
A 24-year-old man has a sister with adult polycystic kidney disease. He asks you if he should be screened for the disease. What is the most appropriate screening test?
98.
Which of the following tests is most useful in the assessment of pancreatic exocrine function?
99.
Which one of the following is an example of a lung neuroendocrine tumor?
100.
A 65 year old male with a history of hypertension presents with oliguria and a serum creatinine of 3.2mg/dL (baseline 1.1mg/dL). Urinalysis shows muddy brown casts. What is the most likely cause of his condition?
