Category Haematology

Haemolytic Anaemia

Schistocytes and helmet cells

Overview Hemolytic anemia is simply anemia due to the destruction of red blood cells. The destruction of red blood cells happens at an accelerated pace, beyond the capacity of the…...

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Macrocytic Anaemia

Macro-ovalocytes

Overview Macrocytic anemia is characterized by Low Hb and High MCV (> 100). B12 and folate are required for the maturation of RBCs. Immature RBCs are larger, hence the increase…...

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Microcytic Anaemia

Basophilic stippling

Overview Microcytic anemia is characterized by low hemoglobin and low mean corpuscular volume. It is very important to confirm the cause of anemia, starting with a peripheral blood smear and…...

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Anaemia

Conjunctival pallor

Anaemia is defined as a decrease in red cell mass as evidenced by low haemoglobin concentration in blood below the reference range for a given age or sex in a…...

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Introduction to Haematology and Blood Transfusion

Peripheral blood smear

Centrifugation Serum Plasma Definition Liquid that remains after blood has clotted Liquid that remains when clotting is prevented Preparation Centrifuge clotted blood Centrifuge whole blood with anticoagulant Fibrinogen Absent Present…...

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Massive Transfusion and Transfusion Reactions

Massive Transfusion Massive transfusion is defined as the administration of greater than 1 total blood volume (10 – 20 units of blood) in 24 hours or replacing 1/2 of the…...

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Transfusion Therapy

Pre-Transfusion Testing Group and Screen (Type and Screen) Antigens that are not present in screened cells are unlikely to cause significant hemolytic reactions (0.2% risk of transfusion reaction if only…...

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TOTW #23 – Haematology

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TOTW #8 – Haematology

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