As regards membranous proteins, distinguish between carrier proteins, channel proteins, and pumps Carrier proteins Channels Pumps Function Binds specific molecules and changes their conformation to transport them across the cell…...
You must be a Hyperexcision Explorer member to access this content.
… Hyperexcision Explorer Membership Required You must be a Hyperexcision Explorer member to access this content.Join NowAlready a member? Log in here...
You must be a Hyperexcision Explorer member to access this content.
Overview Plasma cell disorders involve the abnormal proliferation of plasma cells. These B-cell clones synthesize and secrete a single monoclonal immunoglobulin or its fragments e.g. free light chains, and free…...
You must be a Hyperexcision Explorer member to access this content.
Overview Lymphomas are tumors arising from lymphoid cells. They have a much less dramatic presentation than leukemias. They are classified into 2 major groups – Hodgkin’s and Non-Hodgkin’s – based…...
You must be a Hyperexcision Explorer member to access this content.
Myelodysplastic syndromes are characterized by dysplastic and ineffective hematopoiesis – bone marrow failure**.** It is sometimes described as “pre-leukemic” since there is a risk of transformation into acute leukemia (30%).…...
You must be a Hyperexcision Explorer member to access this content.
Overview Myeloproliferative neoplasms are abnormal proliferations of one or more terminal myeloid cell lines in the peripheral blood (RBCs, WBCs, platelets). Myeloproliferative neoplasms are poorly characterized and poorly undersood. They…...
You must be a Hyperexcision Explorer member to access this content.
CLL is characterized by a progressive accumulation of monoclonal, mature, non-functional B lymphocytes. CLL is usually discovered on routine blood tests as an isolated lymphocytosis. It is defined by a…...
You must be a Hyperexcision Explorer member to access this content.
Overview Acute Leukemia is an abnormal proliferation of blasts in either the peripheral myeloid or lymphoid cell lines. Acute Leukemias are of rapid onset. The blasts dramatically affect the bone…...
You must be a Hyperexcision Explorer member to access this content.
Hematological malignancies are clonal diseases (neoplasms) that are derived from a single hematopoietic stem cell or peripheral lymphoid tissue that has undergone a genetic alteration (e.g. B cell Lymphoma)… Hyperexcision…...
You must be a Hyperexcision Explorer member to access this content.
Overview Sickle cell disease is a hereditary, autosomal recessive disease caused by a point mutation of the beta-globin gene resulting in the absence of HbA and the production of HbS.…...
You must be a Hyperexcision Explorer member to access this content.