Amblyopia

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Amblyopia is a disorder of the ocular-neural tracts resulting in decreased visual acuity in one or both eyes. It is usually as a results from disorders in the eye itself. It is difficult to elicit symptoms of Amblyopia in infants, hence history and physical exam are important. Diagnosis is via a formal optometric examination. Treatment involves correcting the cause and patching the non-amblyogenic eye. Results are best seen in young and compliant patients.

Types of Amblyopia according to cause

Type of amblyopiaDescription
Strabismic amblyopiaAmblyopia in the non-dominant eye of the strabismic patient
Refractive amblyopiaAmblyopia in the eye with worse refractive error
Deprivation amblyopiaAmblyopia due to ptosis or long-standing opacities which interfere with proper use of the retina
Toxic amblyopiaAmblyopia secondary to Vitamin Deficiency (e.g. Folate), Lead toxicity, Methanol poisoning, chloramphenicol, ethambutol and digoxin
  • Pathophysiology
    • The brain suppresses images from a poorly-seeing eye due to inequivalent images (overlapping image, poor quality etc.).
    • This results in an irreversible degree of cortical blindness in the affected eye.
  • Signs and symptoms
    • Decreased visual acuity during routine exam
    • Poor vision
    • Blurry vision
    • Difficulty distinguishing letters/numbers
    • Clues in infants
      • Features of strabismus
      • Unequal red-reflex
      • Lenticular opacities
      • FHx of pediatric eye disease
  • Treatment
    • Remove any cataracts or opacities
    • Correct refractive errors with corrective lenses
    • Patch the non-amblyogenic eye
    • Strabismus surgery
Eye-patch on the non-amblyogenic eye eye

Jeffrey Kalei
Jeffrey Kalei
Articles: 335

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