Outline the host, organ affected, mode of transmission and diseases caused by the different species of Chlamydia
| C.Trachomatis A-C | C. Trachomatis D-K | C. Trachomatis L1-L3 | Chlamydophila pneumoniae | Chlamydophila psittaci | |
|---|---|---|---|---|---|
| Natural host | Human | Human | Human | Human | Birds (Parrot) |
| Organ affected | Eyes | Eyes, Genitourinary tract, Lungs | Genitourinary tract, Anorectum | Lungs | Lungs |
| Mode of transmission | Discharge from eyes or nose, Direct contact, Fomites, Insects | Sexual intercourse, Vertical | Sexual intercourse | Aerosolized respiratory secretions | Airbone through bird dander |
| Disease | Trachoma | Neonatal conjunctivitis, Neonatal pneumonia, Cervicitis, Proctitis, Pelvic inflammatory disease, Reactive arthritis | Lymphogranuloma venerium | Pneumonia | Psittacosis, Pneumonia |
- Briefly describe the life-cycle of chlamydia
- Elementary body attaches to a host cell
- Elementary body enters the host body surrounded by a vacuole (Inclusion)
- Transforms into a larger more metabolically active reticulate body
- Modifies the inclusion into a more hospitable environment for rapid replication BY BINARY FISSION over 30-72 hours
- Multiplication ceases
- Massive number of reticulate bodies reorgnaises into elementary bodies
- Multiplication ceases, the host cell ruptures and releases elementary bodies into the environment
- New elementary bodies are shed in semen or secretions to attach to new host cells
- Outline the complications of chlamydial infections
- Complications of pneumonia:
- Respiratory failure
- Myocarditis
- Endocarditis
- Meningoencephalitis
- Hepatitis
- Complications of Genitourinary infection:
- PID
- Fitz-Hugh-Curtis syndrome
- Ectopic pregnancy
- Reactive arthritis
- Infertility
- Perinatal transmission causing conjunctivitis
- otitis media
- pneumonia
- Complications of lymphogranuloma venereum:
- strictures in anogenital tract
- Genital elephantiasis
- Infertility
- Complications of pneumonia:
